Results 191 to 200 of about 184,920 (263)

The Mediating Role of Psychological Capital Between Caring Behaviour and Work Engagement of Nurses: A Cross-Sectional Study. [PDF]

Nurs Open
Tian W, Zhang GW, Song GQ.
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Low-Temperature Lignin-Derived Carbon Electrodes Enabled by a Natural Casein Binder for Lithium-Ion, Sodium-Ion Batteries and Supercapacitors. [PDF]

Materials (Basel)
Gross X, Kurc B, Rudnicka E, Tomasz J, Galiński M.   +4 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Quantitative design principles for biofunctional metal-organic frameworks: Stability thresholds, biointerface energetics, and therapeutic applications. [PDF]

Mater Today Bio
Bohlooli M, Khajeh M, Ghaffari-Moghaddam M, Pakdel A.   +3 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Qualitative study of barriers and facilitators to Dietary Approaches to Stop Hypertension (DASH) on the Caribbean island of Montserrat. [PDF]

BMJ Public Health
Berners-Lee B, Duberry N, Hazel-Blake D, Mallen C, Shepherd T, Tirion AS, Weston D, Greenaway-Duberry S, Pae R.   +8 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Comparative Three-Dimensional Finite Element Analysis of Stress Distribution and Deformation in Endodontically Treated Maxillary Premolars Restored With Composite and Different Fibre Reinforcement Strategies. [PDF]

Cureus
Arora G, Gill S, Damor P, Goyal S, Karndhar D.   +4 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source