Results 41 to 50 of about 181,443 (264)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural Reasons for School Violence and Education Strategies

open access: yesCenter for Educational Policy Studies Journal, 2020
For the purposes of the research, we developed a concept of structural reasons that we theoretically assume appear as typical structural reasons for violence in schools.
Janez Krek
doaj   +1 more source

Numerical Investigation of the Post-Fire Performance of Steel Columns

open access: yesBuildings, 2022
Research on the seismic performance of steel structures has led to the development of improved structures, which minimize structural and non-structural damage and can be reused immediately after an earthquake.
Dafni Pantousa   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Investigation of the Effect of Wall Thickness and Wall Height on Building Behaviour During an Earthquake

open access: yesBuildings
Earthquake effects were investigated in single-story masonry buildings with walls of different heights and thicknesses. Five different masonry building models were created, with wall thicknesses ranging from 16 cm to 32 cm and wall heights ranging from ...
Tuncay Kap
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The structure of the brain and human behaviour

open access: yesPedagogy and Psychology of Sport, 2018
Currently, the state of knowing the structure and functionality of the human brain is a source of interest for many researchers. Despite the fact that there are significant advances in neurobiology, there is still a lack of information on neuroanatomy and neurophysiology that could shed a new look at interpersonal behavior.
openaire   +6 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Relevance of structural brain connectivity to learning and recovery from stroke

open access: yesFrontiers in Systems Neuroscience, 2010
The physical structure of white matter fibre bundles constrains their function. Any behaviour that relies on transmission of signals along a particular pathway will therefore be influenced by the structural condition of that pathway.
Heidi Johansen-berg   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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