Results 51 to 60 of about 181,443 (264)

The ARoS Rainbow Panorama – Curved Glass as a Load Bearing Element

Challenging Glass Conference Proceedings, 2010
A ring-shaped, tubular steel/glass structure resting on 14 columns, diameter 52m, is one main part of the art object ”ARoS Rainbow Panorama” by Olafur Eliasson on top of the ARoS building in Aarhus, Denmark. The inner and outer walls with a total area of
S. Greiner
doaj   +1 more source

A Study on the Flexural Behaviour of Geopolymer Lightweight Eco-Friendly Concrete Using Coconut Shell as Coarse Aggregate

Advances in Civil Engineering, 2021
This paper presents the flexural behaviour of concrete containing ground granulated blast furnace slag (GGBS) as a binder, manufactured sand (M-sand) as a fine aggregate, and coconut shell (CS) and crushed stone aggregate (CSA) as coarse aggregates ...
S. Nithya, K. Gunasekaran, G. Sankar
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Experimental analysis of aluminium/carbon epoxy hybrid laminates under flexural load

Fracture and Structural Integrity, 2019
Industry needs new materials that present very high structural characteristic, such as high strength, low weight and high damage tolerance. To obtain these characteristics a new class of materials has been introduced: Fibre Metal Laminate (FML); they ...
Costanzo Bellini, Vittorio Di Cocco, Francesco Iacoviello, Luca Sorrentino   +3 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Shared attention in virtual immersive reality enhances electrophysiological correlates of implicit sensory learning

Scientific Reports
Shared attention effects on learning and memory demonstrate that experiences are amplified when we are not alone. Virtual reality poses new challenges to the study of co-presence.
Pietro Sarasso, Irene Ronga, Francesca Piovesan, Paolo Barbieri, Elena Del Fante, Daniela De Luca, Ludovico Bechis, Anna Osello, Katiuscia Sacco   +8 more
doaj   +1 more source

Language Problems and ADHD Symptoms: How Specific Are the Links?

Brain Sciences, 2016
Symptoms of inattention and hyperactivity frequently co-occur with language difficulties in both clinical and community samples. We explore the specificity and strength of these associations in a heterogeneous sample of 254 children aged 5 to 15 years ...
Erin Hawkins, Susan Gathercole, Duncan Astle, The CALM Team, Joni Holmes   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source