Results 201 to 210 of about 1,929,146 (335)

Towards expanding the capabilities of structural biology with the Molecular dynamics (MD) simulations [PDF]

Mariia Nemchinova
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Structural biology of Helicobacter pylori type IV secretion system [PDF]

, 2006
Alessandro Angelini, Laura Cendron, Anke Seydel, Nicola Barison, T. Tosi, Roberto Battistutta, Giuseppe Zanotti   +6 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Optimization of the prostaglandin F2α receptor for structural biology. [PDF]

PLoS One
Salze M, Chrétien S, Boora TS, Macovei M, Barbeau E, Blais V, Laporte SA, Audet M.   +7 more
europepmc   +1 more source

Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15)

, 2015
Igor Ivanov, Hartmut Kühn, Dagmar Heydeck   +2 more
openalex   +2 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Structural biology of HIV-1 reverse transcriptase allosteric inhibitors for drug design. [PDF]

Acta Pharm Sin B
Zhou Z, Sun Y, Feng D, Wang Z, Zhao F, Gao S, Zhan P, Kang D, Liu X.   +8 more
europepmc   +1 more source

The Coming Extinction of Homo Economicus and the Eclipse of the Chicago School of Antitrust: Applying Evolutionary Biology to Structural and Behavioral Antitrust Analyses

, 2011
Thomas J. Horton
openalex   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source