Results 211 to 220 of about 1,910,238 (232)

Deciphering the Structural Biology of GFAP: Connotations of Its Potency in Presaging the Diagnosis for Traumatic Brain Injury and AD. [PDF]

Neurol Int
Kanuri SH, Sirrkay PJ.
europepmc   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Present and future structural biology activities at DESY and the European XFEL. [PDF]

J Synchrotron Radiat
Oberthür D, Hakanpää J, Chatziefthymiou S, Pompidor G, Bean R, Chapman HN, Weckert E.   +6 more
europepmc   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview. [PDF]

J Synchrotron Radiat
McCarthy AA, Basu S, Bernaudat F, Blakeley MP, Bowler MW, Carpentier P, Effantin G, Engilberge S, Flot D, Gabel F, Gajdos L, Kamps JJAG, Kandiah E, Linares R, Martel A, Melnikov I, Mossou E, Mueller-Dieckmann C, Nanao M, Nurizzo D, Pernot P, Popov A, Royant A, de Sanctis D, Schoehn G, Talon R, Tully MD, Soler-Lopez M.   +27 more
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

ALS-ENABLE: creating synergy and opportunity at the Advanced Light Source synchrotron structural biology beamlines. [PDF]

J Synchrotron Radiat
Ralston CY, Gupta S, Del Mundo JT, Soe AC, Russell B, Rad B, Tyler J, Paul S, Kahan DN, Kristensen LG, Subramanian S, Kidd S, Burnett K, Sankaran B, Classen S, Prigozhin DM, Taylor JR, Dickert JM, Royal KB, Rozales A, Ortega SL, Allaire M, Nix JC, Hura GL, Holton JM, Hammel M, Adams PD.   +26 more
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source