Results 201 to 210 of about 899,634 (266)
aGPCR-HEK: A Stable High-Expression Inducible Mammalian Cell Expression System for Adhesion GPCR Structural Biology Applications. [PDF]
Bio ProtocFavara DM, Tate CG.
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Microcrystals in structural biology: small samples, big insights. [PDF]
IUCrJOberthür D.
europepmc +1 more source
Poxvirus structural biology for application to vaccine design. [PDF]
Trends ImmunolYu H, Resch W, Moss B.
europepmc +1 more source
The Structural Biology of T-Cell Antigen Detection at Close Contacts. [PDF]
Immunol RevLui Y +5 more
europepmc +1 more source
An integrative structural biology approach to identify the binding mode of a nanobody towards the pea ascorbate peroxidase. [PDF]
Comput Struct Biotechnol JD'Ercole C +3 more
europepmc +1 more source