Results 51 to 60 of about 2,365 (218)
Nonlinear Modeling of Structural Breaks Concerning Money Demand Function in Iran Using Fuzzy Approach [PDF]
پژوهشهای اقتصادی, 2014 The main purpose of this paper is to introduce a method for more accurately measurement of structural breaks’ impacts of money demand function using fuzzy set approach.
Esmaiel Abounoori, Behnam Shahryar
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Estimation of heterogeneous panels with structural breaks [PDF]
Journal of Econometrics, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Baltagi, Badi Hani, Feng, Q., Kao, C.
openaire +3 more sources
Algorithms, 2020 This paper develops the generalized causality algorithm and applies it to a multitude of data from the fields of economics and finance. Specifically, our parameter-free algorithm efficiently determines the optimal non-linear mapping and identifies ...
Johannes Stübinger, Katharina Adler
doaj +1 more source
Ekoist Journal of Econometrics and Statistics, 2022 Accurate forecasts about the future are vital in time series analyses, but accurately modeling complex structures in the data is always challenging. Two major sources of complexity are autoregressive conditional heteroskedasticity (ARCH) effects on data ...
Daud Ali Aser, Esin Firuzan
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Static and Dynamic Structural Symmetry Breaking [PDF]
, 2006 We reconsider the idea of structural symmetry breaking (SSB) for constraint satisfaction problems (CSPs). We show that the dynamic dominance checks used in symmetry breaking by dominance-detection search for CSPs with piecewise variable and value symmetries have a static counterpart: there exists a set of constraints that can be posted at the root node
Pierre Flener +3 more
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source