Results 111 to 120 of about 1,643,550 (313)

Market Integration: Case Studies of Structural Change

open access: yes
The grain/oilseed industry is undergoing considerable structural change through mergers and new value-added businesses, which raises price-related questions.
Franken, Jason R.V.   +3 more
core   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Validating multiple structural change models : A case study [PDF]

open access: yes
In a recent article, Bai and Perron (2003, Journal of Applied Econometrics) present a comprehensive discussion of computational aspects of multiple structural change models along with several empirical examples.
Zeileis, Achim, Kleiber, Christian
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Structural Change and Economic Dynamics

open access: yes, 2018
Structural Change and Economic Dynamics publishes articles about theoretical and applied, historical and methodological aspects of structural change in economic systems.
Roberto Scazzieri
core  

Distributive impact of structural change : does environmental degradation matter?

open access: yes, 2009
Vulnerability to reduction of natural capital depends on defensive substitution possibilities that, in turn, are affected by the availability of other productive factors.
RUSSU, Paolo   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Role of Small Farms in Structural Change

open access: yes
This paper explains regionally differentiated patterns of structural change based on a theoretical framework dealing with strategic interaction of farms on the land market.
Margarian, Anne, Huettel, Silke
core   +2 more sources

The Concept of Information Sharing Behaviors in Complex Organizations: Research in Latvian Enterprises [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2016
The purpose of this paper is to explore the factors influencing behaviors of information sharing in complex organizations. Evaluation of the previous studies on provision of information turnover process and the role of organizational culture in ...
Andrejs Cekuls
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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