Results 11 to 20 of about 2,083,635 (328)

Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

open access: yesNature Communications, 2021
Rpn13 is a substrate receptor of the 26S proteasome and an anti-cancer drug target. Here, the authors identify and characterize XL5, a lead compound that binds to the N-terminal Pru domain of human Rpn13 (hRpn13), solve the NMR structure of XL5-ligated ...
Xiuxiu Lu   +20 more
doaj   +1 more source

A combined evolutionary and structural approach to disclose the primary structural determinants essential for proneurotrophins biological functions

open access: yesComputational and Structural Biotechnology Journal, 2021
The neurotrophins, i.e., Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), Neurotrophin 3 (NT3) and Neurotrophin 4 (NT4), are known to play a range of crucial functions in the developing and adult peripheral and central nervous systems.
S. Covaceuszach   +3 more
doaj   +1 more source

Characterizing polygonality in biological structures [PDF]

open access: yesPhysical Review E, 2006
Several systems involve spatial arrangements of elements such as molecules or cells, the characterization of which bears important implications to biological and physical investigations. Traditional approaches to quantify spatial order and regularity have relied on nearest neighbor distances or the number of sides of cells.
Costa, Luciano da Fontoura   +2 more
openaire   +3 more sources

Systematic Comparison of Structural Characterization of Polysaccharides from Ziziphus Jujuba cv. Muzao

open access: yesMolecules, 2023
To investigate the structural information differences of Ziziphus Jujuba cv. Muzao polysaccharides, ten samples were successfully extracted from aqueous and alkaline solutions, prepared via DEAE-Sepharose Fast Flow through different eluents and Sephacryl
Xiaolong Ji   +6 more
doaj   +1 more source

Protein structure search and local structure characterization [PDF]

open access: yesBMC Bioinformatics, 2008
Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3D) protein structures increases, a greater variety of studies can be conducted with increasing efficiency, among which is the design of protein structural alphabets.
Ku Shih-Yen, Hu Yuh-Jyh
openaire   +3 more sources

Structural identifiability of viscoelastic mechanical systems [PDF]

open access: yes, 2014
We solve the local and global structural identifiability problems for viscoelastic mechanical models represented by networks of springs and dashpots. We propose a very simple characterization of both local and global structural identifiability based on ...
Mahdi, Adam   +2 more
core   +8 more sources

Characterization of the Structure of Saudi Crude Asphaltenes by X-ray Diffraction [PDF]

open access: yes, 1997
Structural characterization studies have been carried out on four commercial Saudi Arabian crude oils. The aromaticity and crystallite parameters of the asphaltenes were studied by X-ray diffraction methods and compared to the average structural ...
Ali, Mohammad F.   +2 more
core   +4 more sources

Structural characterization of polysaccharide from jujube (Ziziphus jujuba Mill.) fruit

open access: yesChemical and Biological Technologies in Agriculture, 2021
Highlights Structural characteristics of PZMP4 were analyzed by HPGPC, GC, FT-IR, GC-MS, NMR, SEM and AFM. PZMP4 mainly consisted of (1→4)-linked GalpA with three branches boned to O-3.
Xiaolong Ji   +5 more
doaj   +1 more source

Processing and characterization of CaTiO3 perovskite ceramics [PDF]

open access: yesProcessing and Application of Ceramics, 2014
Calcium titanate (CaTiO3) ceramics with perovskite structure were produced by solid state reaction. Calcium carbonate (CaCO3) and titanium dioxide (TiO2) were mixed (in molar ratios 1/1 and 3/2), and the obtained mixtures were calcined at 1150 °C in ...
Guilherme Gralik   +4 more
doaj   +1 more source

A Structurally Characterized Fluoroalkyne

open access: yesAngewandte Chemie, 2017
AbstractThe facile synthesis of a stable and isolable compound with a fluoroalkynyl group, M−C≡CF, is reported. Reaction of [Ru(C≡CH)(η5‐C5Me5)(dppe)] with an electrophilic fluorinating agent (NFSI) results in the formation of the fluorovinylidene complex [Ru(=C=CHF)(η5‐C5Me5)(dppe)][N(SO2Ph)2].
Lewis M. Hall   +5 more
openaire   +4 more sources

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