Results 81 to 90 of about 6,005,558 (266)

Advances and unresolved challenges in the structural characterization of isomeric lipids

, 2017
As the field of lipidomics grows and its application becomes wide and varied it is important that we don't forget its foundation, i.e. the identification and measurement of molecular lipids.
Batarseh, Amani, Mitchell, Todd W., Abbott, Sarah K., Poad, Berwyck L.J., Hancock, Sarah E.   +4 more
core   +1 more source

A structural and functional model for human bone sialoprotein [PDF]

, 2013
Human bone sialoprotein (BSP) is an essential component of the extracellular matrix of bone. It is thought to be the primary nucleator of hydroxyapatite crystallization, and is known to bind to hydroxyapatite, collagen, and cells.
Durrant, Marcus, Vincent, Kevin
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Expression and characterization of E-LecEGF for structural study and assay development [PDF]

, 2009
Human E-selectin (hE-selectin) is a cell adhesion molecule expressed on the membrane of endothelial cells. It is a C-type lectin whose key role is to mediate the initial rolling and adhering of leukocytes in the leukocyte recruitment in inflammation and ...
Yu, Jing
core   +1 more source

Extraction, purification, structural characterization, bioactivities, modifications and structure–activity relationship of polysaccharides from Ophiopogon japonicus: a review

Frontiers in Nutrition
Ophiopogon japonicus (Thunb.) Ker Gawl., is a traditional Chinese medicine (TCM) with a history of thousands of years. O. japonicus polysaccharides (OJPs), as one of the main active ingredient, are a kind of representative pharmacological bioactive ...
Yiqiang Zhang, Bo Chen, Bo Chen, Hua Zhang, Juan Zhang, Juan Xue, Juan Xue   +6 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Structural failures in buildings

, 1984
12.00; first published 1981Available from British Library Document Supply Centre- DSC:86/16582(Structural) / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Institution of Structural Engineers (ISE), London (United Kingdom)
core  

Purification and structural characterization of atypical dextran-type capsular exopolysaccharide from Lactobacillus gasseri ATCC 33323

Chemical and Biological Technologies in Agriculture
Background Probiotic strain Lactobacillus gasseri (L. gasseri) is widely used in the food industry due to its diverse bioactive activities, in which the exopolysaccharide (EPS) is a key functional component. While the secreted EPS from L.
Huazhi Tang, Zixin Ye, Mingsheng Chen, Xiaotong Yang, Chengcheng Song, Guihua Tai, Yifa Zhou, Sisi Cui, Liangnan Cui   +8 more
doaj   +1 more source