Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
An optimized protocol for plant extracellular vesicles isolation from Ophiopogon japonicus root: a comparative evaluation based on miRNA cargo. [PDF]
Xiao Y +9 more
europepmc +1 more source
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang +7 more
wiley +1 more source
Expression and characterization of Est2: a novel cold-adapted esterase from Antarctic bacterium defining the new esterase family XXII. [PDF]
He Y +6 more
europepmc +1 more source
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai +12 more
wiley +1 more source
Characterization and expression analysis of transcription factors in <i>Spartina alterniflora</i> unveil their critical roles in salt stress resistance. [PDF]
Jiang Y +6 more
europepmc +1 more source
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou +8 more
wiley +1 more source
Laboratory detection and rotational spectroscopy of <i>trans</i>-HNSO: implications for astronomical observations. [PDF]
Lattanzi V +4 more
europepmc +1 more source
A Degradable Bioinspired Flier with Aerogel‐Based Colorimetric Sensors for Environmental Monitoring
Biodegradable fliers are developed inspired by Tipuana tipu samaras, integrating cellulose nanocrystal aerogel (CNCa) sensors loaded with natural dyes for pH and ammonia detection. The lightweight, degradable fliers mimic natural morphology and aerodynamics, offering an eco‐friendly, scalable solution for in situ environmental monitoring after passive ...
Gianpaolo Gallo +4 more
wiley +1 more source
Genomic characterization of Staphylococcus epidermidis Se252 isolated from the rhizosphere of a Brazilian endemic plant. [PDF]
Sanchez AB +16 more
europepmc +1 more source

