Results 81 to 90 of about 4,015,508 (257)

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Exploring Ecological and Social Forms of Connectivity in Kespukwitk, Nova Scotia

, 2021
Connectivity is an essential component of conservation efforts. Ambiguity surrounding the term makes distinguishing between multiple forms difficult, posing challenges to implementation.
Griffin, Alysha
core  

Structural Connectivity Shaped by Cryospheric Degradation Modulates Sediment Transport Dynamics in High Mountain Asia

Water Resources Research
Rapid atmospheric warming has transformed cryospheric landscapes, affecting sediment transport processes. However, our understanding of hillslope and riverine connectivity in large headwaters remains limited. Here, we apply the Index of Connectivity (IC)
Jinlong Li, Genxu Wang, Jiapei Ma, Peng Huang, Chunlin Song, Shouqin Sun, Linmao Guo, Kai Li, Haoyu Wang, Dongfeng Li, Admin Husic   +10 more
doaj   +1 more source

Complementing Engel Classification: Postoperative Scalp EEG as an Objective Indicator in SEEG‐Guided Radiofrequency Thermocoagulation—A Seizure‐Onset Pattern‐Based Stratified Analysis—

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) is a minimally invasive therapy for drug‐resistant focal epilepsy. However, the relationship between specific seizure‐onset patterns (SOPs), particularly low‐voltage fast activity (LVFA), and postoperative scalp EEG normalization remains inadequately ...
Yi‐qing Yang, Rui Zhang, Haiyan Ma, Lu Yang, Xuefeng Qu, Qiqi Chen, Yan Zhang   +6 more
wiley   +1 more source

Dynamic BOLD functional connectivity in humans and its electrophysiological correlates [PDF]

, 2012
Neural oscillations subserve many human perceptual and cognitive operations. Accordingly, brain functional connectivity is not static in time, but fluctuates dynamically following the synchronization and desynchronization of neural populations.
Verena Brodbeck, Laufs, Helmut, Wegner, Frederic von, Morzelewski, Astrid, Enzo eTagliazucchi, Astrid Morzelewski, Helmut Laufs, Verena eBrodbeck, Helmut eLaufs, Frederic eVon Wegner, Frederic von Wegner, Astrid eMorzelewski, Enzo Tagliazucchi, Tagliazucchi, Enzo, Brodbeck, Verena   +14 more
core   +1 more source

White Matter Structural Connectivity Is Not Correlated to Cortical Resting-State Functional Connectivity over the Healthy Adult Lifespan

Frontiers in Aging Neuroscience, 2017
Structural connectivity (SC) of white matter (WM) and functional connectivity (FC) of cortical regions undergo changes in normal aging. As WM tracts form the underlying anatomical architecture that connects regions within resting state networks (RSNs ...
Adrian Tsang, Adrian Tsang, Adrian Tsang, Catherine A. Lebel, Catherine A. Lebel, Catherine A. Lebel, Signe L. Bray, Signe L. Bray, Signe L. Bray, Bradley G. Goodyear, Bradley G. Goodyear, Bradley G. Goodyear, Moiz Hafeez, Moiz Hafeez, Moiz Hafeez, Roberto C. Sotero, Cheryl R. McCreary, Cheryl R. McCreary, Cheryl R. McCreary, Richard Frayne, Richard Frayne, Richard Frayne   +21 more
doaj   +1 more source

Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch, Hannah Schwartz, Kimberly H. Markowitz, Abhishek Jaywant, Christopher D. Hildenbrand, Jai Perumal, Ulrike W. Kaunzner, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Association of structural connectivity with functional brain network segregation in a middle-aged to elderly population

Frontiers in Aging Neuroscience
IntroductionThe deterioration of white matter pathways is one of the hallmarks of the ageing brain. In theory, this decrease in structural integrity leads to disconnection between regions of brain networks and thus to altered functional connectivity and ...
Maximilian Schulz, Marvin Petersen, Bastian Cheng, Götz Thomalla   +3 more
doaj   +1 more source

The UCLA Multimodal Connectivity Database: A web-based platform for brain connectivity matrix sharing and analysis

Frontiers in Neuroinformatics, 2012
Brain connectomics research has rapidly expanded using functional MRI (fMRI) and diffusion-weighted MRI (dwMRI). A common product of these varied analyses is a connectivity matrix (CM).
Jesse A. Brown, Jeffrey D. Rudie, Anita eBandrowski, John D. Van Horn, Susan Y Bookheimer   +4 more
doaj   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source