Results 41 to 50 of about 4,792,487 (297)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Sorting out Sortilins: structural studies on the VPS10 family [PDF]
, 2017 The topic of this dissertation is the structural characterization of the VPS10 receptors Sortilin and SorCS2, as well as their interactions with proneurotrophins.
Sub Crystal and Structural Chemistry +2 more
core
Banber Erevani Hamalsarani. Sots'iologiaHousing policy is widely framed as a key mechanism of socio-economic integration in contexts of forced displacement; however, theoretical debates increasingly distinguish between processes and outcomes, challenging the assumption that formal access ...
Mira Antonyan
doaj +1 more source
Image completion via transformation and structural constraints
EURASIP Journal on Image and Video Processing, 2020 Image completion is an approach to fill a damaged region (hole) in an image. In this study, we adopt a novel method which can repair a target region with structural constraints in an architectural scene. An objective function that consists of three terms
Qiaochuan Chen +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Applied Sciences, 2023 To analyze the impact of different objective functions and additive manufacturing (AM) constraints on structural topology optimization, it is necessary to perform an in-depth comparative study.
Babin Dangal, Sangjin Jung
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Structural constraints identified with covariation analysis in ribosomal RNA. [PDF]
PLoS ONE, 2012 Covariation analysis is used to identify those positions with similar patterns of sequence variation in an alignment of RNA sequences. These constraints on the evolution of two positions are usually associated with a base pair in a helix.
Lei Shang +3 more
doaj +1 more source