Results 71 to 80 of about 4,792,487 (297)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Structural Modelling of Financial Constraints on Investment: Where Do We Stand? [PDF]

open access: yes
This paper surveys issues with respect to the structural modelling of econometric tests of investment facing financial constraints, to their link with firms data and asset prices, and to their consequences for macroeconomic modelling. The key issue is to
Jean-Bernard Chatelain
core  

Underwater image matching by incorporating structural constraints

open access: yesInternational Journal of Advanced Robotic Systems, 2017
Underwater robot plays an important role in underwater perception and manipulation tasks. Vision information processing is essential for the intelligent perception of an underwater robot, in which image matching is a fundamental topic.
Xu Yang   +6 more
doaj   +1 more source

Stability constraints on large-scale structural brain networks

open access: yesFrontiers in Computational Neuroscience, 2013
Stability is an important dynamical property of complex systems and underpins a broad range of coherent self-organized behaviour. Based on evidence that some neurological disorders correspond to linear instabilities,we hypothesize that stability ...
Richard T. Gray   +3 more
doaj   +1 more source

The Left-Left Constraint: A structural constraint on adjuncts

open access: yes, 2022
Left-hand adjuncts of left-headed (= head-initial) phrases are constrained in a particular way. The constraint, which is absent for adjuncts of head-final phrases, is this. The head of the adjunct must be in the absolute phrase-final position. Anything that follows the head disqualifies the phrase as an adjunct. The effect of this head-final-constraint
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Structural modelling of investment and financial constraints: Where do we stand? [PDF]

open access: yes
This paper surveys issues with respect to the structural modelling of econometric tests of investment facing financial constraints, to their link with firms data and assets prices, and to their impact in macroeconomic modelling.
Jean-Bernard Chatelain
core  

Representation and Management of the Constraints in Incremental Databases [PDF]

open access: yes, 2002
Ihis paper extends the bundle to be able to represent the constraint condition. The bundle is a container of objects and/or other bundles, while an object is a unit representing the entity in the database that is created in the bottom-up manner, and is ...
KOBE, Sadayuki   +2 more
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Mechanics of Optimal Structural Design for Extreme Loads to Peak System Responses [PDF]

open access: yes, 2015
Over the past decades, with the development of modern manufacturing and information technology, demands of smart and economical structural designs have been increasing considerably. Central to this engineering issue is that a good structural design needs
Wang, Chien-Kai   +4 more
core  

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