Results 51 to 60 of about 3,448,461 (253)

The hippocampal network model: A transdiagnostic metaconnectomic approach

NeuroImage: Clinical, 2018
Purpose: The hippocampus plays a central role in cognitive and affective processes and is commonly implicated in neurodegenerative diseases. Our study aimed to identify and describe a hippocampal network model (HNM) using trans-diagnostic MRI data from ...
Eithan Kotkowski, Larry R. Price, P. Mickle Fox, Thomas J. Vanasse, Peter T. Fox   +4 more
doaj   +1 more source

Type 2 Diabetes Mellitus May Exacerbate Gray Matter Atrophy in Patients With Early-Onset Mild Cognitive Impairment

Frontiers in Neuroscience, 2020
BackgroundThe precise physiopathological association between the courses of neurodegeneration and cognitive decline in type 2 diabetes mellitus (T2DM) remains unclear.
Chang Li, Chang Li, Zhiwei Zuo, Daihong Liu, Rui Jiang, Yang Li, Haitao Li, Xuntao Yin, Yuqi Lai, Jian Wang, Kunlin Xiong   +10 more
doaj   +1 more source

Parkinson’s disease may disrupt overlapping subthalamic nucleus and pallidal motor networks

NeuroImage: Clinical, 2023
There is an ongoing debate about differential clinical outcome and associated adverse effects of deep brain stimulation (DBS) in Parkinson’s disease (PD) targeting the subthalamic nucleus (STN) or the globus pallidus pars interna (GPi).
Alejandro N. Santos, Ferath Kherif, Lester Melie-Garcia, Antoine Lutti, Alessio Chiappini, Laurèl Rauschenbach, Thiemo F. Dinger, Christoph Riess, Amir El Rahal, Marvin Darkwah Oppong, Ulrich Sure, Philipp Dammann, Bogdan Draganski   +12 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Comparative Analysis of Choroid Plexus Volume Between MOG Antibody Associated Disease and Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun, Shaun G. Hong, Na Young Park, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

On the Use of Formative Measurement Specifications in Structural Equation Modeling: A Monte Carlo Simulation Study to Compare Covariance-Based and Partial Least Squares Model Estimation Methodologies [PDF]

The broader goal of this paper is to provide social researchers with some analytical guidelines when investigating structural equation models (SEM) with predominantly a formative specification. This research is the first to investigate the robustness and
Ringle, Christian M., Wilson, Bradley, Götz, Oliver, Wetzels, Martin   +3 more
core   +2 more sources

Selective disrupted gray matter volume covariance of amygdala subregions in schizophrenia

Frontiers in Psychiatry
ObjectiveAlthough extensive structural and functional abnormalities have been reported in schizophrenia, the gray matter volume (GMV) covariance of the amygdala remain unknown.
Zhongyu Chang, Liping Liu, Liyuan Lin, Gang Wang, Chen Zhang, Hongjun Tian, Wei Liu, Lina Wang, Bin Zhang, Juanjuan Ren, Yu Zhang, Yingying Xie, Xiaotong Du, Xiaotong Wei, Luli Wei, Yun Luo, Haoyang Dong, Xin Li, Zhen Zhao, Meng Liang, Congpei Zhang, Xijin Wang, Chunshui Yu, Chunshui Yu, Chunshui Yu, Wen Qin, Huaigui Liu   +26 more
doaj   +1 more source

Nonparametric estimation of covariance functions by model selection [PDF]

, 2009
We propose a model selection approach for covariance estimation of a stochastic process. Under very general assumptions, observing i.i.d replications of the process at fixed observation points, we construct an estimator of the covariance function by ...
Muniz Alvarez, Lilian, Muñiz-Alvarez, Lilian, Biscay, Rolando, Lilian, Muniz-Alvarez, Jérémie Bigot, Lilian Muñiz-Alvarez, Bigot, Jérémie, Rolando Biscay, Jean-Michel Loubes, Loubes, Jean-Michel   +9 more
core   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source