Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network [PDF]
Background Mild cognitive impairment (MCI) is a heterogeneous disorder with significant individual variabilities in clinical and biological features. Abnormal inter-regional structural covariance suggests disruption of the brain structural network in MCI.
Xiaotong Wei +6 more
doaj +4 more sources
Connectome-based predictive modeling of smoking severity using individualized structural covariance network in smokers [PDF]
IntroductionAbnormal interactions among distributed brain systems are implicated in the mechanisms of nicotine addiction. However, the relationship between the structural covariance network, a measure of brain connectivity, and smoking severity remains ...
Weijian Wang +8 more
doaj +4 more sources
Analysis of brain structural covariance network in Cushing disease [PDF]
Background: Cushing disease (CD) is a rare clinical neuroendocrine disease. CD is characterized by abnormal hypercortisolism induced by a pituitary adenoma with the secretion of adrenocorticotropic hormone.
Can-Xin Xu +7 more
doaj +3 more sources
Structural Covariance Network Disruption and Functional Compensation in Parkinson’s Disease [PDF]
Purpose: To investigate the structural covariance network disruption in Parkinson’s disease (PD), and explore the functional alterations of disrupted structural covariance network.Methods: A cohort of 100 PD patients and 70 healthy participants underwent
Cheng Zhou +13 more
doaj +2 more sources
Exploring the core network of the structural covariance network in childhood absence epilepsy [PDF]
Childhood absence epilepsy (CAE) is a generalized pediatric epilepsy, which is generally considered to be a benign condition since most children become seizure-free before reaching adulthood. However, cognitive deficits and changes of brain morphological
Merel J.A. Eussen +8 more
doaj +2 more sources
Causal Structural Covariance Network Suggesting Structural Alterations Progression in Type 2 Diabetes Patients [PDF]
Background and PurposeAccording to reports, type 2 diabetes (T2D) is a progressive disease. However, no known research has examined the progressive brain structural changes associated with T2D.
Jiang Zhang +15 more
doaj +2 more sources
Topological abnormality of structural covariance network in MRI-negative frontal lobe epilepsy [PDF]
BackgroundFrontal lobe epilepsy (FLE) is the second most common type of focal epilepsy, however, imaging studies of FLE have been far less than Temporal lobe epilepsy (TLE) and the structural findings were not consistent in previous literature ...
Yin Liu +11 more
doaj +2 more sources
Structural covariance networks across the life span, from 6 to 94 years of age [PDF]
Structural covariance examines covariation of gray matter morphology between brain regions and across individuals. Despite significant interest in the influence of age on structural covariance patterns, no study to date has provided a complete life span ...
Elizabeth DuPre, R. Nathan Spreng
doaj +2 more sources
Impaired Topological Properties of Gray Matter Structural Covariance Network in Epilepsy Children With Generalized Tonic–Clonic Seizures: A Graph Theoretical Analysis [PDF]
Modern network science has provided exciting new opportunities for understanding the human brain as a complex network of interacting regions. The improved knowledge of human brain network architecture has made it possible for clinicians to detect the ...
Yongxin Li +6 more
doaj +2 more sources
Hippocampal morphological atrophy and distinct patterns of structural covariance network in Alzheimer’s disease and mild cognitive impairment [PDF]
Elucidating distinct morphological atrophy patterns of Alzheimer’s disease (AD) and its prodromal stage, namely, mild cognitive impairment (MCI) helps to improve early diagnosis and medical intervention of AD. On that account, we aimed to obtain distinct
Dawei Miao +4 more
doaj +2 more sources

