Results 131 to 140 of about 4,034,259 (329)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Optimum structural design with static aeroelastic constraints [PDF]
The static aeroelastic performance characteristics, divergence velocity, control effectiveness and lift effectiveness are considered in obtaining an optimum weight structure. A typical swept wing structure is used with upper and lower skins, spar and rib
Bowman, Keith B +2 more
core +1 more source
Structural Intuition and Creative Play: An Architectural Perspective to Shell Pedagogies [PDF]
, 2016 The notions of structural intuition and creative play had been raised by particular structural artists (Billington, 1983 [1]). Professor Pier Luigi Nervi expressed the importance of Structural Intuition in his 1965 Elliot Norton Lectures at Harvard ...
Tang, Gabriel
core
Design of Structural Members for Crashworthiness Using Three Dimensional Topology Optimization
, 2003 Kohei Yuge, Susumu Ejima, Junichi Abe
openalex +2 more sources
Structural design and motion analysis of Hexapod Bionic walking device [PDF]
, 2016 Zhifang Zhu
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
X-29A aircraft structural loads flight testing [PDF]
The X-29A research and technology demonstrator aircraft has completed a highly successful multiphase flight test program. The primary research objective was to safely explore, evaluate, and validate a number of aerodynamic, structural, and flight control
Mccrosson, Paul +3 more
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
STAEBL: Structural tailoring of engine blades, phase 2 [PDF]
The Structural Tailoring of Engine Blades (STAEBL) program was initiated at NASA Lewis Research Center in 1980 to introduce optimal structural tailoring into the design process for aircraft gas turbine engine blades.
Brown, K. W., Hirschbein, M. S.
core +1 more source