Results 61 to 70 of about 6,591,436 (258)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
UNDERSTANDING, TYPES AND STRUCTURAL ELEMENTS OF ELECTORAL SYSTEMS [PDF]
Discussion about elections and electoral systems is in fact discussion about the effects of representative bodies in democratic political systems. Understanding of that link is not possible without knowing technical details used for forming electoral ...
Gordana Iličić
doaj
The Ilimsky Ostrog in the Taltsy Museum of Wooden Architecture near Irkutsk
Based on archive and field studies of the remained fragments of the fort (Spasskaya gate tower and a chapel), the article considers an attempt to restore its plan structure and different objects: a shopping arcade, a writ hut, a complex of the tsar’s ...
Nikolai Kradin
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Ferritic stainless steels in structural applications [PDF]
Ferritic stainless steels are low cost, price-stable, corrosion-resistant materials. Although widely used in the automotive and domestic appliance sectors, structural applications are scarce owing to a dearth of performance data and design guidance.
Cashell, KA, Baddoo, NR
core +1 more source
The meaning, origin and use of masonry pendentives at the early Christian architecture [PDF]
The construction and function of the masonry pendentives, defined as a triangular section of a sphere, have been extensively examined. However, its genesis and the very conceptual definition continue to raise doubts.
Marković Ivica
doaj
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reliability and Safety of Structural Elements in the Gigacycle Region of Loading
The authors of this paper, based on their own results, discuss fatigue properties of low-alloyed fine-grained steel STRENX 700MC obtained in the ultra-high-cycle region (gigacycle fatigue) with regard to the reliability and safety of structural elements.
Libor Trsko +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Challenges in the design of concrete structures with reclaimed elements
The European Green Deal published by the European Commission in December 2019 has set the target of 50% reduction of CO2 emissions and primary material consumptionby 2030 compared to the 1990 levels.
Allaix, D.L. +3 more
core

