Results 71 to 80 of about 6,591,436 (258)
Validation of Indian standard code provisions for fire resistance of flexural elements [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2015 Fire resistance provisions in Indian codes are prescriptive in nature and provide only tabulated fire ratings for structural members. Eurocode EN 1992-1-2:2004 suggests simplified methods which include explicit equations for fire resistant design.
Aneesha Balaji +2 more
doaj
Геодинамика и тектонофизика, 2015 In terms of tectonics, the Deryugin basin (Fig. 1) is a part of the epi-Mesozoic Okhotsk plate comprising the heterogeneous basement that is mainly pre-Cenozoic (the lower structural stage) and the sedimentary cover that is mainly represented by the ...
V. P. Semakin, A. V. Kochergin
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Library of digital models and constructive simulations of structural elements. [PDF]
, 2023 The aim of this communication is to describe the use of new technologies to obtain a library of digital models of structural elements and construction simulations to improve learning processes in the sujects of concrete structures and foundations.
Sánchez-Berrocal, Juan +1 more
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Jurnal Teknik Sipil dan Perencanaan, 2016 The construction of Building F Universitas Pekalongan consists of 8 levels. It used Contruction and Planning regulation of SK SNI T-15-1991-03 especially about structural concrete works.
Endah Kanti Pangestuti +3 more
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome [PDF]
, 2013 A key signature of module exchange in the genome is phase symmetry of exons, suggestive of exon shuffling events that occurred without disrupting translation reading frame.
Kalmár, Lajos +2 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source