Results 161 to 170 of about 8,779,764 (343)
Structural engineer to structural engineer: conversation with Steve Johnston [PDF]
The Structural Design of Tall Buildings, 2001 Chris D. Poland, James O. Malley
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
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Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
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FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
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Learning structural engineering [PDF]
, 2010 Tim Ibell, Bath University, shares views on the structural engineering education during the Structural Engineering in the 21st Century academic conference. Students has realized that that good structural design is not about sizing members or following codified rules but is about producing a structural concept which leads to the satisfaction of a set of
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Application of finite-element-based solution technologies for viscoplastic structural analyses [PDF]
Finite-element solution technology developed for use in conjunction with advanced viscoplastic models is described. The development of such solution technology is necessary for performing stress/life analyses of engineering structural problems where the ...
Arya, V. K.
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Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
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Art and Structural Engineering-Art of Structural Engineering
, 2011 Beyond the classical dispute between architects and engineers, it is a matter of fact that art and engineering are not only compatible, but also for some cases indissociable. This communication aims to contribute to the debate. In the first part the experience of artists is exemplified in terms of influence on structural engineering : Pevsner and ...
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