Results 141 to 150 of about 855,547 (311)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Engineering Bulk Photovoltaic Effect in 2D Transition Metal Dichalcogenides
Advanced ScienceA promising method for producing photocurrents above the Shockley–Queisser limit in non‐centrosymmetric materials is the bulk photovoltaic effect (BPVE), especially in low‐dimensional materials.
Sikandar Aftab, Arden L. Moore
doaj +1 more source
Advanced structural wind engineering
, 2013 This book serves as a textbook for advanced courses as it introduces state-of-the-art information and the latest research results on diverse problems in the structural wind engineering field. The topics include wind climates, design wind speed estimation,
Kareem, Ahsan, Tamura, Yukio
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
4th Fraunhofer LBF Meeting on Structural Durability in Railway Engineering 2006
, 2022 Vorträge des 4th International Meeting on Structural Durability in Railway Engineering: - Forschung und Entwicklung innovativer Schienenradsätze - Bemessungsaspekte ausgehend von der Wöhlerlinie nach dem Stand der Technik - Auslegung und Bewertung von ...
core
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Seismic resilience: Innovations in structural engineering for earthquake-prone areas
Open EngineeringThe contemporary structural engineering notion of "seismic resilience" is to yield a public to its pre-earthquake state in precise time. The goal of our research is the OMRF (Ordinary Moment Resisting Frame), which is mid-rise building that had exposed ...
Al-Asadi Ali K., Alrebeh Salih
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Structural Health Monitoring Strategies for Smart Sensor Networks
, 2008 Structural health monitoring (SHM) is an emerging field in civil engineering, offering the potential for continuous and periodic assessment of the safety and integrity of civil infrastructure.
Spencer, Billie F., Jr., Gao, Yong
core