Results 131 to 140 of about 855,547 (311)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Silicon–carbon composite anodes for lithium-ion batteries: synthesis, architecture, interfacial regulation, and practical prospects

Frontiers in Mechanical Engineering
Silicon–carbon composite anodes are among the most intensively studied candidates for next-generation lithium-ion batteries because they combine the high theoretical capacity of silicon with the conductivity, structural resilience, and processability of ...
Xianzheng Liu, Guangyuan Wang, Wenxiang Du, Chao Jin, Xiaoming Liu   +4 more
doaj   +1 more source

Structural motion engineering

, 2014
This innovative volume provides a systematic treatment of the basic concepts and computational procedures for structural motion design and engineering for civil installations. The authors illustrate the application of motion control to a wide spectrum of
Laflamme, Simon, Connor, Jerome
core   +1 more source

Social Challenges of Structural Engineering

Structural Engineering International, 2016
Preface
openaire   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

CYBERBRIDGE: AN INTERACTIVE TOOL TO PROMOTE ACTIVE LEARNING IN STRUCTURAL ENGINEERING COURSES [Elektronisk resurs]

, 2018
Understanding basic concepts and assumptions is a crucial step in the learning process of any subject, yet today it is not always achieved. A change of the current teaching method is suggested in this paper through the implementation of new learning ...
Fernandez, Ignasi,, Gil Berrocal, Carlos,   +1 more
core  

Structural Engineering Global Interoperability: Knowledge Sharing

, 2017
<p>Design and engineering work for global projects has increased exponentially in the last two decades and will continue to grow as globalization accelerates.
Iyad Alsamsam, Mustafa Mahamid, Anne Ellis   +2 more
core   +1 more source

Engineering the 3D structure of organoids

Stem Cell Reports
Organoids form through the sel f-organizing capabilities of stem cells to produce a variety of differentiated cell and tissue types. Most organoid models, however, are limited in terms of the structure and function of the tissues that form, in part because it is difficult to regulate the cell type, arrangement, and cell-cell/cell-matrix interactions ...
Samuel P. Moss, Ezgi Bakirci, Adam W. Feinberg   +2 more
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Mechanical characteristics of pile cap foundations for offshore wind farms

Shenzhen Daxue xuebao. Ligong ban
In order to investigate the force transmission mechanism of offshore high pile cap foundation under large bending moment loads from wind turbine units and complex marine environmental loads, we use a step-by-step loading method in a numerical model to ...
ZHU Zhoujie, ZHAN Yide, MA Bin, WANG Haijun, ZHANG Xiaoxue, LI Bingxuan   +5 more
doaj   +1 more source