Results 131 to 140 of about 8,779,764 (343)

Properties and performance of high strength fibre reinforced concrete by using steel and polypropylene fibres [PDF]

open access: yes, 2019
Many reinforced concrete structures suffer severe degradation due to the effect from freezing and thawing, shrinkage and expansion, aggressive environment, earthquake and drastic increase of live loads.
Wan Jusoh, Wan Amizah
core  

From individual behaviour to an evaluation of the collective evolution of crowds along footbridges

open access: yes, 2016
This paper proposes a crowd dynamic macroscopic model grounded on microscopic phenomenological observations which are upscaled by means of a formal mathematical procedure.
Bruno, Luca   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Seismic vulnerability of existing buildings: non-invasive approach for dynamic behaviour assessment

open access: yesGEOmedia, 2018
This paper presents a brief overview of the concept of seismic risk, with particular regard to existing civil buildings. Given that the seismic risk can be expressed as a combination involving seismic hazard and seismic vulnerability, these aspects are ...
Gianluca Acunzo   +2 more
doaj  

Probabilistic simulation of the human factor in structural reliability [PDF]

open access: yes
Many structural failures have occasionally been attributed to human factors in engineering design, analyses maintenance, and fabrication processes. Every facet of the engineering process is heavily governed by human factors and the degree of uncertainty ...
Chamis, Christos C., Shah, Ashwin R.
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Editorial: Methods and applications in computational methods in structural engineering

open access: yesFrontiers in Built Environment, 2023
Alejandro Jiménez Rios   +3 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A Neuro-Symbolic Framework for Ensuring Deterministic Reliability in AI-Assisted Structural Engineering: The SYNAPSE Architecture

open access: yesBuildings
This paper addresses the opportunities and risks of integrating Large Language Models (LLMs) into structural engineering. Exclusive reliance on LLMs is inadequate in this field, because their probabilistic nature can lead to hallucinations and ...
Adriano Castagnone, Giuseppe Nitti
doaj   +1 more source

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