The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Structural engineering, BSA binding and computational analysis of isonipacotate based enzyme inhibitors containing 1,2,4-triazole. [PDF]
Virk NA +7 more
europepmc +1 more source
Shaking Table Attached to Magnetorheological Damper: Simulation and Experiments for Structural Engineering. [PDF]
Vargas AN +5 more
europepmc +1 more source
UNH Structural Engineering Professor Available to Comment on Roof Collapses [PDF]
Potier, Beth
core +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Structural Engineering of Tyrosine-Based Neuroprotective Peptides: A New Strategy for Efficient Blood-Brain Barrier Penetration. [PDF]
Li Z, Zhu Q, Qiao Y, Fu J, Tao L, Min W.
europepmc +1 more source
Laminated Structural Engineering Strategy toward Carbon Nanotube-Based Aerogel Films. [PDF]
Fu C, Sheng Z, Zhang X.
europepmc +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
3D-Printed Carbon-Based Electrochemical Energy Storage Devices: Material Design, Structural Engineering, and Application Frontiers. [PDF]
Dong Y +7 more
europepmc +1 more source
Atomic-Level Structural Engineering of Graphene on a Mesoscopic Scale. [PDF]
Trentino A +6 more
europepmc +1 more source

