Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Structural Engineering of Bimetallic CoCe-ZIF Derives Catalysts with Optimized Electronic Structure for Enhanced Oxygen Electrocatalysis. [PDF]
Zhou L+7 more
europepmc +1 more source
Establishing the linkages between structural engineering and risk management
Dave Brunsdon
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The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source
UiO-66 Metal-Organic Framework Membranes: Structural Engineering for Separation Applications. [PDF]
Sun Y.
europepmc +1 more source
Hydrogel‐Based Capacitive Sensor Model for Ammonium Monitoring in Aquaculture
Traditional techniques for monitoring aquaculture water quality, particularly ammonium levels, harm fish. This work presents a novel capacitive sensor with an ionic hydrogel transducer to monitor ammonium concentration in real time based on the ammonium‐induced hydrogel dissociation and osmotic pressure. Monitoring aquaculture water quality, especially
Mohammad Mirzaee+3 more
wiley +1 more source
Structural engineering of flagellin as vaccine adjuvant: quest for the minimal domain of flagellin for TLR5 activation. [PDF]
Afzal H, Murtaza A, Cheng LT.
europepmc +1 more source
New Horizons of Structural Engineering and Its Contributions to Society
Tsutomu Usami, Tetsuhiko Ueda
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Engineering ESPT Pathways Based on Structural Analysis of LSSmKate Red Fluorescent Proteins with Large Stokes Shift [PDF]
Kiryl D. Piatkevich+3 more
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Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani+2 more
wiley +1 more source