Results 31 to 40 of about 17,948,787 (263)

Artificial intelligence-based novel design charts for doubly reinforced concrete beams

open access: yesJournal of Asian Architecture and Building Engineering, 2022
This study proposes artificial neural networks (ANNs) that can solve structural engineering problems in general and design ductile concrete beams in particular.
Won-Kee Hong   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

E-newsletter school of civil engineering: student's achievements-istructe student prize for excellence in structural engineering [PDF]

open access: yes, 2023
Nur Syahira Binti Anwar, a student from the School of Civil Engineering at UiTM, has been awarded the prestigious IStructE Student Prize. The Institution of Structural Engineers (IStructE), the world's leading professional body for structural engineering,
UiTM, College of Engineering
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Current Research Topics: Railroad Bridges and Structural Engineering [PDF]

open access: yes, 2012
Railroad infrastructure must be maintained safely and reliably for both owners and users. Railroad bridge expenditures in particular represent about 10% of the annual capital investment for Class I railroads in the United States (U.S.).
Moreu, Fernando, LaFave, James M.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Heat treatment design guided by semi-supervised learning for strength-ductility optimization in an Al-Cu-Li alloy

open access: yesMaterials & Design
This study presents a semi-supervised learning-guided strategy for designing a dual-stage aging schedule for an Al-Cu-Li alloy, enabling decoupled control of T1 and θ′ precipitates. By integrating active learning and self-training, the approach optimizes
Lyu Jing   +11 more
doaj   +1 more source

Data Processing of Laser Scans Towards Applications in Structural Engineering [PDF]

open access: yes, 2009
This research is investigating the use of high resolution 3D terrestrial laser scanners as tools to capture geometric data of complex scenes for structural engineering applications. Laser scan technology is continuously improving, with commonly available
Walsh, Sara B.   +3 more
core  

Structural behaviour of high strength S690 cold-formed structural hollow sections under compression

open access: yes, 2023
16th East Asian-Pacific Conference on Structural Engineering and Construction, 3-6 Dec 2019, Brisbane, Australia202310 bcchAccepted ManuscriptRGCOthersResearch Committee and the Chinese National Engineering Research Centre for Steel Construction (Hong ...
Xiao, M, Chung, KF
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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