Results 41 to 50 of about 17,948,787 (263)
The influence of Al addition on the synergistic enhancement of erosion-corrosion resistance and mechanical strength of cupronickel alloys was systematically studied.
Yi Yuan +9 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
To enhance the specific modulus of aerospace structural materials, this study employs machine learning methods to optimize the micro-alloying composition of Al–Li alloys. A total of 151 alloy composition-elastic modulus samples were analyzed.
Lyu Jing +8 more
doaj +1 more source
DUCTILITY AND STRENGTH OF REINFORCED CONCRETE BEAMS INTRINSICALLY REINFORCED WITH POLYPROPYLENE FIBRES [PDF]
The Thirteenth East Asia-Pacific Conference on Structural Engineering and Construction (EASEC-13), September 11-13, 2013, Sapporo ...
GHOSNI, N. +8 more
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
ON THE THREAT OF SUPPLIERS FOR THE ENGINEERING CONSULTING AND DESIGN SERVICES FIRMS [PDF]
In the case of companies from engineering consulting and design services industry the classic models of analysis (e.g. Porter's five forces for structural analysis) exhibit interesting aspects in comparison with the situation when applied to traditional ...
Gabriel Sorin STROE
doaj
PERFORMANCE OF POLYMER-CONCRETE COMPOSITES EXPOSED TO SEVERE ENVIRONMENT [PDF]
The Thirteenth East Asia-Pacific Conference on Structural Engineering and Construction (EASEC-13), September 11-13, 2013, Sapporo ...
Nejadi, S +8 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Effects of general structural stress on vibrational power flow
Vibrational power flow contains two types of information, namely, vibration velocity and structural internal force, and is an important parameter for measuring vibration level and transmission.
Hongdong Wang +3 more
doaj +1 more source

