Results 41 to 50 of about 822,257 (312)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Second Generation of Active Structural Control in Civil Engineering
Computer-Aided Civil and Infrastructure Engineering, 1996 : Research and development in active control of civil engineering structures in the United States has approximately a 20-year history. Under the leadership of the U.S. National Science Foundation in forming the U.S. Panel on Structural Control Research and in launching a program initiative in the area of structural control, there has been a surge of ...
G.W. Housner, T.T. Soong, S.F. Masri
openaire +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Materials & DesignThis study presents a semi-supervised learning-guided strategy for designing a dual-stage aging schedule for an Al-Cu-Li alloy, enabling decoupled control of T1 and θ′ precipitates. By integrating active learning and self-training, the approach optimizes
Lyu Jing +11 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Materials & DesignThe influence of Al addition on the synergistic enhancement of erosion-corrosion resistance and mechanical strength of cupronickel alloys was systematically studied.
Yi Yuan +9 more
doaj +1 more source
ON THE THREAT OF SUPPLIERS FOR THE ENGINEERING CONSULTING AND DESIGN SERVICES FIRMS [PDF]
Risk in Contemporary Economy, 2014 In the case of companies from engineering consulting and design services industry the classic models of analysis (e.g. Porter's five forces for structural analysis) exhibit interesting aspects in comparison with the situation when applied to traditional ...
Gabriel Sorin STROE
doaj