Results 61 to 70 of about 1,624,721 (312)
Applications of generative design in structural engineering [PDF]
Revista ingeniería de construcción, 2021 G. Díaz +3 more
openaire +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Engineering Structures and Technologies, 2015 This paper presents an engineering survey based on experience of the authors during design and expertise of complex building structures in period of 2000–2014.
Michail Samofalov, Vytautas Papinigis
doaj +1 more source
Rock mass structural surface trace extraction based on transfer learning
Open Geosciences, 2022 To solve engineering geological problems, including water conservancy, transportation, and mining, it is necessary to obtain information on rock mass structures, such as slopes, foundation pits, and tunnels, in time.
Yi Xuefeng +6 more
doaj +1 more source
Bannan Engineering Laboratories Redesign [PDF]
, 2014 Due to the growing student body within Santa Clara University\u27s School of Engineering, an increase in classrooms, laboratories, offices, and study spaces is needed to for student engineering resources.
Candelaria, Pia Johanna +2 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Analysis of the free vibration of a coupled plate/fluid interacting system and interpretation using sub-system modal energy [PDF]
, 2007 This paper describes a method for describing and quantifying the vibratory behaviour of interacting structural/fluid systems based upon reference to the relative energy associated with each of the sub-systems.
Gorman, Daniel G., Horáček, J.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Data-Driven Exploration of Sc-Induced mechanical enhancement in Al-Cu-Li alloys
Materials & DesignA data-driven strategy was developed to identify microalloying elements that simultaneously enhance the yield strength, elongation, and elastic modulus of Al-Cu-Li alloys. Among 71 T6-tempered compositions, Sc was identified as the most promising element
Lyu Jing +7 more
doaj +1 more source
Yantu gongcheng xuebao, 2018 The seismic advanced detection of tunnels is a common method to estimate faults, karst caves and other adverse geologies, and is an important method to guarantee the safety of tunnel construction.
CHEN Lei 1, LI Shu-cai 1, LIU Bin 1, LI Ming 1, XU Xin-ji 1, LI Ning-bo 2, NIE Li-chao 1
doaj +1 more source