Results 71 to 80 of about 1,624,721 (312)

Improving Loss Estimation for Woodframe Buildings. Volume 2: Appendices [PDF]

, 2002
This report documents Tasks 4.1 and 4.5 of the CUREE-Caltech Woodframe Project. It presents a theoretical and empirical methodology for creating probabilistic relationships between seismic shaking severity and physical damage and loss for buildings in ...
Beck, James L., Boyd, Tom, Porter, Keith A., Scawthorn, Charles R., Seligson, Hope A., Tobin, L. Thomas, Young, Ray   +6 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Review of the Synergies Between Computational Modeling and Experimental Characterization of Materials Across Length Scales

, 2015
With the increasing interplay between experimental and computational approaches at multiple length scales, new research directions are emerging in materials science and computational mechanics.
Dingreville, Rémi, Karnesky, Richard A., Puel, Guillaume, Schmitt, Jean-Hubert   +3 more
core   +3 more sources

A Vector Matroid-Theoretic Approach in the Study of Structural Controllability Over F(z) [PDF]

, 2017
In this paper, the structural controllability of the systems over F(z) is studied using a new mathematical method-matroids. Firstly, a vector matroid is defined over F(z). Secondly, the full rank conditions of [sI-A|B] are derived in terms of the concept
Chen, Ying, Chen, Yongzhi, Li, Zhixiong, Reza, Malekian, Yuan, Yupeng   +4 more
core   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Reliability verification of an existing reinforced concrete slab [PDF]

, 2018
The submitted contribution provides background information on the principles accepted in the CEN Technical Specification (TS). The application of the verification methods provided in the TS is clarified by an assessment of a reinforced concrete ...
Holický, Milan, Jung, Karel
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Prediction of seismic-induced structural damage using artificial neural networks [PDF]

, 2008
Peer ...
De Lautour, Oliver Richard, Omenzetter, Piotr   +1 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Prediction of Scour Depth for Diverse Pier Shapes Utilizing Two-Dimensional Hydraulic Engineering Center’s River Analysis System Sediment Model

Fluids
Examining scouring around bridge piers is crucial for ensuring water-related infrastructure’s long-term safety and stability. Accurate forecasting models are essential for addressing scour, especially in complex water systems where traditional methods ...
Muhanad Al-Jubouri, Richard P. Ray, Ethar H. Abbas   +2 more
doaj   +1 more source