Results 31 to 40 of about 20,133 (313)

Improving the cost performance of green buildings based on soft system methodology and value engineering [PDF]

Archives of Civil Engineering
The rising demand for sustainable construction practices has prompted a focus on optimizing the cost performance of green buildings. This study investigates enhancing green cost performance by employing the Soft Systems Methodology (SSM), Value ...
Sutikno Sutikno, Sarwono Hardjomuljadi, Henny Wiyanto   +2 more
doaj   +1 more source

FEM modeling of spatial structural systems in evaluation of the real structural performances [PDF]

Facta Universitatis. Series: Architecture and Civil Engineering, 2011
The paper is a review of enhanced concept of CASA (Computer Aided Structural Analysis) software application in FEM modeling of spatial structural systems of bridges, buildings, industrial facilities, machine devices, etc.
Kovačević Dušan, Ranković Slobodan
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Numerical Methods for Topological Optimization of Wooden Structural Elements

Buildings
Timber represents a building material that aligns with the environmental demands on the impact of the construction sector on climate change. The most common engineering solution for modern timber buildings with large spans is glued laminate timber ...
Daniela Țăpuși, Andrei-Dan Sabău, Adrian-Alexandru Savu, Ruxandra-Irina Erbașu, Ioana Teodorescu   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Monitoring and Control of Structural Vibrations

Applied Sciences
Monitoring and control of structural vibrations are crucial to ensure structural safety and vibration comfort of civil engineering structures, such as buildings, bridges, tunnels, antennas, stadia etc [...]
Felix Weber
doaj   +1 more source

The Diagnostics of the Condition and Management of Large-Panel Buildings Using Point Clouds and Building Information Modelling (BIM)

Buildings, 2023
Technological developments involving the implementation of modern measuring equipment and the digitalisation of civil engineering can contribute to extending the service life of buildings. Large-panel buildings constitute a large housing stock throughout
Maciej Wardach, Joanna Agnieszka Pawłowicz, Marta Kosior-Kazberuk, Janusz Ryszard Krentowski   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source