Results 91 to 100 of about 6,381,275 (336)

On flexibility [PDF]

open access: yes
By building on theoretical work by Mills and Schumann (1985) and Ungern-Sternberg (1990) this paper provides evidence on the determinants of two dimensions of flexibility, the flexibility in adjusting aggregate output over time (tactical flexibility) as ...
Weiss, Christoph R., Briglauer, Wolfgang
core  

Agility and flexibility: what's the difference? [PDF]

open access: yes, 1996
There is growing interest in the concept of “agile organisations” amongst management practitioners and academics. Early publications have been largely practitioner-oriented and have been at pains to claim that this is a new idea, with fundamental ...
Baker, John
core  

Structural flexibility in similar to SbVO4

open access: yes, 2010
similar to SbVO4 is a well known catalyst used for the ammoxidation of propane to acrylonitrile. However, little importance is usually given to the structural flexibility exhibited by the similar to SbVO4 phase, which has rutile-type structure and can ...
Angel R. Landa-Cánovas   +5 more
core   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

A Neurofuzzy Knowledge Model for the Quantification of Structural Flexibility

open access: yes, 2009
An assessment tool in the form of a neurofuzzy knowledge model is proposed, intended to quantitatively express the performance of building structures in relation to the suitability of a building regarding its structural flexibility.
Herwijnen, van, F.   +5 more
core  

SAFlex: A structural alphabet extension to integrate protein structural flexibility and missing data information.

open access: yesPLoS ONE, 2018
In this paper, we describe SAFlex (Structural Alphabet Flexibility), an extension of an existing structural alphabet (HMM-SA), to better explore increasing protein three dimensional structure information by encoding conformations of proteins in case of ...
Ikram Allam   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D

open access: yes, 2014
Human factor D (FD) is a self-inhibited thrombin-like serine proteinase that is critical for amplification of the complement immune response. FD is activated by its substrate through interactions outside the active site.
Sub Crystal and Structural Chemistry   +9 more
core   +1 more source

Structural Flexibility Enables Alternative Maturation, ARGONAUTE Sorting and Activities of miR168, a Global Gene Silencing Regulator in Plants.

open access: yesMolecular Plant, 2018
In eukaryotes, the RNase-III Dicer often produces length/sequence microRNA (miRNA) variants, called "isomiRs", owing to intrinsic structural/sequence determinants of the miRNA precursors (pre-miRNAs).
Taichiro Iki   +7 more
semanticscholar   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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