Results 61 to 70 of about 4,111,048 (252)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Flexibility of Data-Driven Process Structures [PDF]

open access: yes, 2006
The coordination of complex process structures is a fundamental task for enterprises, such as in the automotive industry. Usually, such process structures consist of several (sub-)processes whose execution must be coordinated and synchronized. Effecting this manually is both ineffective and error-prone.
Muller, Dominic   +2 more
openaire   +1 more source

Modelling of structural flexibility of the railway vehicles carbody

open access: yesMATEC Web of Conferences, 2017
The accuracy in the models of railway vehicles in the ride comfort evaluation mainly derives from the modelling of the carbody structural flexibility. The former part of the paper herein reviews the ‘flexible carbody’ type methods used to represent the ...
Dumitriu Mădălina, Crăciun Camil
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Designing Structural Supply Chain Flexibility [PDF]

open access: yes, 2012
In a continuously changing business environment the role of supply chain flexibility is constantly increasing. A flexible supply chain can ensure survival in quickly changing market conditions as well as enable sustainable growth.
Mulinski, K.J.
core  

Damaged Flexibility Matrix Method for Damage Detection of Frame Buildings

open access: yesAdvances in Civil Engineering, 2020
This study presents the damaged flexibility matrix method (DFM) to identify and determine the magnitude of damage in structural elements of plane frame buildings.
Luis S. Vaca Oyola   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Modal flexibility method for structural damage detection in suspension bridges [PDF]

open access: yes, 2014
Suspension bridges meet the steadily growing demand for lighter and longer bridges in today’s infrastructure systems. These bridges are designed to have long life spans, but with age, their main cables and hangers could suffer from corrosion and fatigue.
Chan, Tommy H.T.   +2 more
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Endogenous price flexibility and optimal monetary policy [PDF]

open access: yes, 2014
Much of the literature on optimal monetary policy uses models in which the degree of nominal price flexibility is exogenous. There are, however, good reasons to suppose that the degree of price flexibility adjusts endogenously to changes in monetary ...
Sutherland, Alan   +3 more
core   +1 more source

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