Results 231 to 240 of about 813,020 (358)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

vEMINR: Ultra-Fast Isotropic Reconstruction for Volume Electron Microscopy With Implicit Neural Representation. [PDF]

Adv Sci (Weinh)
Yang J, Huo J, Liu M, Feng C, Zhang Y, Pan G, Meng W, Han R.   +7 more
europepmc   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

FEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo, Emma Piccoli, Luca Bombardi, Martina Aulitto, Salvatore Fusco   +4 more
wiley   +1 more source

Altered Topological Properties of White-Matter Functional Networks in Young Smokers. [PDF]

Addict Biol
Mai Z, Yu D, Huang G, Li X, Wang X, Dong F, Cheng Y, Wang J, Ma Y, Luo L, Yuan K, Xue T.   +11 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

From urban NPOs to rural knowledge networks: applying benefit-sharing models to African genomics research. [PDF]

Nat Commun
Ngwarai N, Tluway F, Mayindi N, Mabasa J, Mashaba G, Khoza S, Hove J, Khoza D, Wafawanaka F, Chipungu S, Ndlovu D, Mdaka B, Ngobeni T, Phiri A, Tibane J, Gómez-Olivé FX, Tollman S, Mkansi VN, Micklesfield LK, Manabile MM, Choma SSR, Kasina P, Burke E, Ramsay M, Fabian J, LeBaron von Baeyer S.   +25 more
europepmc   +1 more source

Charalampos Koutalakis, Cities and the Structural Funds. The Domestic Impact of EU Initiatives for Urban Development, Sak- koulas Publishers, Athens 2003, 304 σελ.

, 2017
Δημήτρης Σκιαδάς, Δημήτρης Ν. Χρυσοχόου   +1 more
openalex   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Evolutionary Diffusion Framework Empowering High-Performance Freeform Terahertz Metasurface Sensing. [PDF]

Sensors (Basel)
Zhang C, Pan M, Hong Q, Shen S, Guo C, Shi Y, Zhang Y.   +6 more
europepmc   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source