Results 31 to 40 of about 813,020 (358)

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk   +9 more
wiley   +1 more source

Allocation of structural funds before and after the brexit: An exercise in the economics of cake-sharing

open access: yesApstract: Applied Studies in Agribusiness and Commerce, 2017
What impact has the Brexit on the allocation of money from the structural funds? As the UK is a net contributor to the EU budget, the budget for Structural and Cohesion Policy will shrink.
Wim Heijman
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

ROMANIAN ADMINISTRATIVE CAPACITY OF EUROPEAN FUNDS ABSOBTION [PDF]

open access: yesCES Working Papers, 2011
The capacity to absorb European funds is part of a state complex integrated admninistrative capacity, a component of a state as a whole. The analysis in this article starts from the theoretical development by studying the reports made by the Romanian ...
Irina Bosie (Ungureanu), Andrei Puica
doaj  

ANALYSIS OF THE ABSORPTION OF EUROPEAN STRUCTURAL AND INVESTMENT FUNDS IN THE NEW MEMBER STATES OF CENTRAL AND EASTERN EUROPE [PDF]

open access: yesAnnals of the University of Oradea: Economic Science
The present research aims to analyze the impact of the allocation of structural and investment funds on regional development in the new member states of Central and Eastern Europe and to identify pragmatic ways to improve absorption, useful in the ...
Bogdan Cosmin MOLDOVAN
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

National Development Plans and Pre-accession Structural Funds: Learning from the Experiences of Ireland [PDF]

open access: yesRomanian Journal of European Affairs, 2002
As it moves towards the new millennium, the Irish economy is impressive not only because of the extent/speed of the transformation and of its growth performance but also due to the fascinating effectiveness in implementing the Structural Funds programmes.
John Bradley
doaj  

Exploratory Study on Absorption and Investment of European Union Structural Funds 2007–2013 by NUTS 2 Level Self-Governments in Poland

open access: yesBarometr Regionalny, 2015
The article provides information on geographical distribution of European Union structural funds among Polish regions (voivodships) analyzing it from various points of view: various kinds of funds, their purposes, amount per inhabitant, as well as the ...
Joanna Rakowska
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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