CONSIDERATIONS ABOUT ABSORPTION OF EUROPEAN FUNDS IN ROMANIA [PDF]
The paper is structured in three chapters, first consisting of general information regarding the type of structural fund and their thematic objectives.
EDUARD EDELHAUSER
doaj
Economic performance of the NUTS III Regions in the Czech Republic in the context of entrepreneurship subsidies from the EU Structural Funds [PDF]
Entrepreneurship is considered to be one of the essential factors of economic growth and entrepreneurship policy is considered to be a significant contributor to the regional economic development.
Jana Kolaříková +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The use of EU funds in Slovakia [PDF]
The paper investigates how funds are allocated by the European Union and how they are used in the Slovak Republic. The paper concentrates on utilizing funds in two regions: Trnava self-governing region and Presov self-governing region, in two periods ...
Igazova Maria
doaj
EUROPEAN STRUCTURAL FUNDS IN ROMANIA: ABSORPTION AND IMPACT ON THE AGRICULTURAL SECTOR [PDF]
The paper proposes an analysis of the effective rate of absorption of European Structural Funds in Romania, allocated to the national agricultural sector, in the period 2019-2022.The research was carried out on the basis of the official information ...
Beatrice-Simona MANOLACHE +2 more
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
THE EU’S COHESION POLICY: LATEST DEVELOPMENTS [PDF]
An analysis and evaluation are made of the evolutionary processes typical for the current regional policy in the EU. Mechanisms of formation and allocation of resources from the structural funds are described.
Lavrovsky B. L. +3 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

