Results 61 to 70 of about 157,215 (260)

Spatial Distribution of EU Structural Funds in Poland in 2004-2006 - Factors, Directions, and Limitations

open access: yesBulletin of Geography. Socio-Economic Series, 2008
In 2004, Poland joined the European Union. This access means the possibility of taking advantage of European Union Structural Funds. Apart from this the structural funds play another important role.
Monika Płaziak, Piotr Trzepacz
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Agriculture, the Structural Funds and the Budget after Enlargement [PDF]

open access: yesRomanian Journal of European Affairs, 2004
The purpose of this article is to examine how the legacy of the, often bruising, negotiations at Copenhagen and subsequently over agriculture will affect the political economy of the European Union and specifically the challenges facing the CAP, the ...
Jim Rollo
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The Assessment of the Effectiveness of the Implementation of Infrastructural Investments within the Regional Operational Programme for the Podkarpackie Province for the years 2007-2013

open access: yesІсторико-політичні проблеми сучасного світу, 2019
This article aims to assess the effects of the implementation of infrastructural investments within the Regional Operational Programme for the Podkarpackie Province for the years 2007-2013.
Войцех Ліхота
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

APPEARANCE ON EUROPEAN UNION POLICY ON FUNDING SOCIO-ECONOMIC DEVELOPMENT [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
In the last years of the current European Union will be involved less in funding developing countries and geographic areas outside it, because we need to focus on eliminating disparities and balancing standards of living in member countries, how much ...
CHIRCULESCU MARIA FELICIA
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The allocation of financial resources of the EU Structural Funds and Cohesion Fund during the period 2007-2013

open access: yesAgricultural Economics (AGRICECON), 2011
The article describes a model to predict the allocation of the EU Structural Funds and the Cohesion Fund over the EU member states. By comparing the predicted allocation with the real allocation, it is possible to indicate which member states receive ...
W. Heijman, T. Koch
doaj   +1 more source

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