Results 81 to 90 of about 814,307 (311)
EU cohesion policy and the role of the regions : investigating the influence of structural funds in the new member states [PDF]
, 2007 This paper undertakes a critical assessment of the influence of the EU Cohesion policy on regionalisation and the role of regional institutions in Central and Eastern Europe.
Bachtler, John, McMaster, Irene
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
STRUCTURAL FUNDS FOR INVESTMENTS BETWEEN 2007-2013 [PDF]
With the integration in the European Union structural funds Romania has reached values close to 28 billion euro for 2007-2013. Funding grants may be between 50% -100% of the investment required for that activity, the difference being the beneficiary's ...
Daniela MIHAI +2 more
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Programmes at the turning point. Challenges, activities and developments for partner regions : September 2003-March 2004 [PDF]
, 2004 This paper looks at structural funds programmes and a range of issues relating to the mid-term of the programmes, with the completion of the mid-term evaluations, the development of proposals for allocating the performance reserve and the mid term ...
Davies, S. +2 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Agricultural Economics (AGRICECON), 2011 The article describes a model to predict the allocation of the EU Structural Funds and the Cohesion Fund over the EU member states. By comparing the predicted allocation with the real allocation, it is possible to indicate which member states receive ...
W. Heijman, T. Koch
doaj +1 more source
Considerations on potential determinants of structural and cohesion funds absorption [PDF]
The importance of ensuring high levels of absorption for the structural and cohesion funds, especially in the deprived regions, is crucial. In such a context, there have been identified the drivers of and possible difficulties associated to the ...
Andreas KOLODZIEJAK +2 more
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
STRUCTURAL FUNDS AND ECONOMIC DIVIDE IN ITALY [PDF]
This paper aims to provide a contribution to the debate on the effectiveness of cohesion policies in Italy. The focus is on the territorial effects of EU spending from 1996 to 2007.
Francesco Aiello, Valeria Pupo
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source