Results 71 to 80 of about 814,307 (311)

Regional devolopment and solidarity in Spain: the relationship between the E.C. and the internal solidarity funds. [PDF]

open access: yes
This paper will analyse the importance that the Regional Solidarity Funds have acquired in the financial systems of those Autonomous Communities able to benefit from them, and the influence that these Funds have had in their development. In addition, the
Ana Isabel González   +2 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

THE MAIN DEFICIENCIES IN THE IMPLEMENTATION OF THE SECTORAL OPERATIONAL PROGRAMME HUMAN RESOURCES DEVELOPMENT [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2013
The absorption of EU funds for Romania is a necessity in the nowadays context. The slow pace of absorption of these structural funds earmarked for Romania as EU member state is a deficiency with negative effects on the economic and social development of ...
Pautu Sorina, Dogaru Madalin, ,
doaj  

The Impact of Structural Funds Policy on European Regions' Growth : A Theoretical and Empirical Approach [PDF]

open access: yes
In this paper, I try to estimate the impact of Structural Funds on the growth rates of Objective 1 European regions during the two first programming periods (1989-2000). I develop a "hybrid" model of economic growth that partially endogenizes the rate of
Mari Carmen Puigcerver-Penalver
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Assessment of the Effectiveness of the Implementation of Infrastructural Investments within the Regional Operational Programme for the Podkarpackie Province for the years 2007-2013

open access: yesІсторико-політичні проблеми сучасного світу, 2019
This article aims to assess the effects of the implementation of infrastructural investments within the Regional Operational Programme for the Podkarpackie Province for the years 2007-2013.
Войцех Ліхота
doaj   +1 more source

ROMANIA - IN SEARCH OF THE EU LOST FUNDS [PDF]

open access: yes
During the 2007- 2013 programming period Romania has been granted 19.6 billion euro of the EU Structural and Cohesion Funds and 8,3 bn euro of EU Agricultural and Fisheries Funds. Unfortunately, the Romanian’s level of absorption of Romania is the lowest
Gabriela DRAGAN
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

APPEARANCE ON EUROPEAN UNION POLICY ON FUNDING SOCIO-ECONOMIC DEVELOPMENT [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
In the last years of the current European Union will be involved less in funding developing countries and geographic areas outside it, because we need to focus on eliminating disparities and balancing standards of living in member countries, how much ...
CHIRCULESCU MARIA FELICIA
doaj  

Does EU Cohesion Policy Promote Growth? Evidence from Regional Data and Alternative Econometric Approaches [PDF]

open access: yes
This paper analyses the growth e®ects of EU structural funds using a new panel dataset of 124 NUTS-1 / NUTS-2 regions over the time period 1995-2005. We extend the current literature with regard to at least three aspects: First of all, we extend the time
Hagen, Tobias, Mohl, Philipp
core  

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