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The Significance of Structural Innovation for Value Alignment and Social Innovation in Faith-Based Organizations: Reinventing Organizations to Dismantle Power Asymmetries

open access: yesDiaconia, 2022
The growing literature on innovation in nonprofit and faith-based organizations (FBO) has focused more on what fosters innovation than what happens after the innovation has been introduced.
Dag-Håkon Eriksen   +1 more
doaj   +1 more source

Modeling, Kinematic Characteristics Analysis and Experimental Testing of an Elliptical Rotor Scraper Pump

open access: yesMachines, 2022
Against the backdrop of the rapid burgeoning of international energy engineering, the efficient utilization of energy is a paramount factor. The key idea in this paper is to propose an elliptical rotor scraper pump (ERSP) in order to address the ...
Zhen Zhang   +6 more
doaj   +1 more source

Integration and evaluation of a meander-shaped fibre-optical sensor in a GFRP leaf spring [PDF]

open access: yesMATEC Web of Conferences, 2021
Fibre-reinforced plastics experience an increasing attention also in the non-aerospace sector. However, the detection of possible internal damage of safety-relevant components remains a challenge.
Janetzko-Preisler Andreas   +8 more
doaj   +1 more source

Pseudoknot length modulates the folding, conformational dynamics, and robustness of Xrn1 resistance of flaviviral xrRNAs

open access: yesNature Communications, 2021
Exoribonuclease-resistant RNAs (xrRNAs) are RNA elements that block the exoribonucleolytic degradation of RNA. Here the authors show how a long-range pseudoknot length modulates the Mg2+-dependence of flaviviral xrRNA’s folding, conformational dynamics ...
Xiaolin Niu   +6 more
doaj   +1 more source

Market Structure And Drug Innovation [PDF]

open access: yesHealth Affairs, 2004
An explosion of knowledge and a growing array of tools and technologies have transformed modern drug R&D, while its cost has risen by a sizable amount. At the same time, the unchecked increase in health care and prescription drug spending has spawned cost containment policies that are restricting the demand for drugs in all major markets.
Pammolli, Fabio, Riccaboni, Massimo
openaire   +5 more sources

Plasma FIB milling for the determination of structures in situ

open access: yesNature Communications, 2023
The authors harness plasma focused ion beams for pseudo-atomic structure determination, reporting increased throughput and automation in in situ structural biology to elucidate structure-function relationships inside cells and tissues.
Casper Berger   +8 more
doaj   +1 more source

Structural Biology of Nanobodies against the Spike Protein of SARS-CoV-2

open access: yesViruses, 2021
Nanobodies are 130 amino acid single-domain antibodies (VHH) derived from the unique heavy-chain-only subclass of Camelid immunogloblins. Their small molecular size, facile expression, high affinity and stability have combined to make them unique ...
Qilong Tang   +2 more
doaj   +1 more source

BIM-Based Energy Analysis and Sustainability Assessment—Application to Portuguese Buildings

open access: yesBuildings, 2021
Buildings are responsible for several negative impacts on the environment, most of them related to nonrenewable energy consumption, increasing the concern regarding buildings energy efficiency. In this context, computer software has been used to estimate
José Pedro Carvalho   +3 more
doaj   +1 more source

Innovation for Inclusive Structural Change [PDF]

open access: yes, 2021
Abstract The chapter proposes the foundations of an analytical framework to identify innovation pathways that lead to inclusive structural change in low- and medium-income countries (LMICs). Innovation pathways depend on how actors, interactions, and conditions affect the origin of innovation; the uptake of the innovations (adoption ...
Ciarli, Tommaso   +2 more
openaire   +2 more sources

Passive mechanical properties of the left ventricular myocardium and extracellular matrix in hearts with chronic volume overload from mitral regurgitation

open access: yesPhysiological Reports, 2022
Cardiac volume overload from mitral regurgitation (MR) is a trigger for left ventricular dilatation, remodeling, and ultimate failure. While the functional and structural adaptations to this overload are known, the adaptation of myocardial mechanical ...
Daniella Corporan   +5 more
doaj   +1 more source

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