Results 41 to 50 of about 5,350,927 (317)
Applied Sciences, 2022 Natural disasters are unavoidable and can cause serious damage to bridges, which may lead to catastrophic losses, both human and economic. Therefore, the assessment of bridges exposed to these events is of paramount importance to identify possible ...
Carlos Mendoza Cabanzo +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Brite innovation survey : executive summary [PDF]
, 2005 This report summarises the fi ndings of an innovation survey\ud of the Australian construction industry undertaken by the\ud BRITE Project of the CRC for Construction Innovation in\ud 2004.
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Structural Analysis with Independent Innovations [PDF]
SSRN Electronic Journal, 2014 Structural innovations in multivariate dynamic systems are typically hidden and often identified by means of a-priori economic reasoning. Under multivariate Gaussian model innovations there is no loss measure available to distinguish alternative orderings of variables or, put differently, between particular identifying restrictions and rotations ...
openaire +2 more sources
Public policy implications of construction innovation research [PDF]
, 2006 This report undertakes an exploratory analysis of Construction Innovation research projects\ud in order to answer the question “What are the public policy implications of Construction\ud Innovation research?
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Demand, challenges, and innovation. Making sense of new trends in innovation policy [PDF]
, 2018 In recent years, the traditional rationale for innovation policy has been expanded to tackling societal challenges. There is also an increasing agreement that demand should be at the core of this challenge-oriented innovation policy, as for innovations ...
Jakob Edler +6 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Nature Communications, 2017 The ESCRT-III and Vps4 complexes mediate a variety of membrane remodelling events. Here the authors describe the structure of the Vps4 hexamer complexed to its cofactor Vta1, and show that Vta1 bridges adjacent Vps4 subunits to promote formation of the ...
Shan Sun +9 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source