The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Nature CommunicationsCryo focused ion beam lamella preparation is a potent tool for in situ structural biology, enabling the study of macromolecules in their native cellular environments.
Casper Berger +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Presentation. Framework conditions, innovation policies and instruments. Seventh Session of the SPECA Project Working Group on Knowledge-based Development and International Conferene on Practical Steps Towards a Knowledge-based Economy [PDF]
, 2015 Session I: Innovation Performance Review of TajikistanThis presentation analyzes innovation framework conditions, policies, and instruments in Tajikistan as part of its Innovation Performance Review.
Stahlecker, Thomas +1 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Presentation. Innovation eerformance review of Tajikistan : selected conclusions and recommendations from chapter 2: national innovation system and innovation governance . Seventh Session of the SPECA Project Working Group on Knowledge-based Development and International Conferene on Practical Steps Towards a Knowledge-based Economy [PDF]
, 2015 This presentation examines the national innovation system and innovation governance of Tajikistan within the framework of innovation for development.
European Alliance for Innovation +1 more
core +1 more source
Scientific ReportsThe primary objective of this research is to propose and examine a technique for accurately determining the azimuth angle of cooperative objects. The proposed methodology aims were to achieve fast processing, increased precision, and enhanced safety.
Rustamaji, Sri Kliwati, Wahyu Widada
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Buildings, 2023 The implementation of condition monitoring for damage identification and the generation of a reliable digital twin are essential elements of preventive conservation.
Eduarda Vila-Chã +2 more
doaj +1 more source