Results 61 to 70 of about 9,782,476 (251)

The local bearing capacity perpendicular to grain of structural timber elements [PDF]

open access: yes, 2012
The accuracy and reliability of empirical models for the local bearing capacity perpendicular to grain of timber beams is questionable as it is not based on any fundamental principal.
Jorissen, A.J.M., Leijten, A.J.M.
core   +2 more sources

Statistical properties and material partial factors of ECC material based on shear failure member

open access: yesFrontiers in Materials
Engineered Cementitious Composite (ECC) material, as a hybrid material, also has uncertainties. In addition, the shear failure mechanism of reinforced ECC (R-ECC) member is different from that of ordinary reinforced concrete (RC) member, and a new ...
Shixiang Yi   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Integrating 3D‐Printed Auxetic Structures for Advanced Concrete Reinforcement

open access: yesAdvanced Materials Interfaces
Reinforced concrete remains integral to modern infrastructure, yet traditional designs, relying on longitudinal reinforcing bars and stirrups, face limitations in adaptability and performance optimization.
Mobin Vandadi   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Structural performance and advantages of DVW reinforced moment transmitting timber joints with steel plate connectors and tube fasteners [PDF]

open access: yes, 2014
This paper presents a study to the moment-rotation aspects of two 3-member DVW reinforced timber connections with an inter-connecting steel plate used as middle member.
Brandon, D.   +4 more
core   +1 more source

Structural Dynamic Analysis of Semi-Submersible Floating Vertical Axis Wind Turbines

open access: yesEnergies, 2016
The strong and stable wind at offshore locations and the increasing demand for energy have made the application of wind turbines in deeper water surge.
Jeremiah Ishie, Kai Wang, Muk Chen Ong
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

BATA LEMPUNG BAHAN BANGUNAN DINDING ALTERNATIF

open access: yesDimensi: Journal of Architecture and Built Environment, 2001
"Bata lempung" is block of wall material, main basic material is sols contains 50-60% clay, pressed and molded, without combusted, used after 28 days and production doesn't depend climates. "Bata lempung" can used as bearing wall or curtain wall, exposed
Vincentius Totok Noerwasito
doaj  

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