Results 61 to 70 of about 3,903,891 (291)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Quantitative characterization of pore structure of several biochars with 3D imaging
Pore space characteristics of biochars may vary depending on the used raw material and processing technology. Pore structure has significant effects on the water retention properties of biochar amended soils.
Hannula, Markus +5 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Aluminum-titanium hydride-boron carbide composite provides lightweight neutron shield material [PDF]
Inexpensive lightweight neutron shield material has high strength and ductility and withstands high internal heat generation rates without excessive thermal stress.
Poindexter, A. M.
core +1 more source
Three-dimensional analysis of reinforced concrete beam-column structures in fire [PDF]
This is the author's accepted manuscript. The final published article is available from the link below. Published version copyright @ 2009 ASCE.In this paper a robust nonlinear finite-element procedure is developed for three-dimensional modeling of ...
Burgess, IW, Huang, Z, Plank, RJ
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Research on the combination of water and membranes as a structural building material [PDF]
p. 3024-3033The aim of this paper is to investigate the combination of water and membranes for temporary architectural applications. Water as a construction material, can be useful for three different purposes: first of all, thanks to its thermal ...
MAFFEI, Roberto +2 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Statistical properties and material partial factors of ECC material based on shear failure member
Engineered Cementitious Composite (ECC) material, as a hybrid material, also has uncertainties. In addition, the shear failure mechanism of reinforced ECC (R-ECC) member is different from that of ordinary reinforced concrete (RC) member, and a new ...
Shixiang Yi +4 more
doaj +1 more source

