Results 71 to 80 of about 3,903,891 (291)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Characterization methods dedicated to nanometer-thick hBN layers

, 2016
Hexagonal boron nitride (hBN) regains interest as a strategic component in graphene engineering and in van der Waals heterostructures built with two dimensional materials.
Barjon, Julien, Fossard, Frederic, Loiseau, Annick, Schue, Leonard, Stenger, Ingrid   +4 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Evaluation of the Tensile Strength of Korean Yellow Poplar Lumber

BioResources
This study was conducted to confirm the feasibility of using yellow poplar, which is a fast-growing hardwood species in Korea, as a structural material.
Chul-Ki Kim, Da-Bin Song, Kug-Bo Shim
doaj   +2 more sources

Integrating 3D‐Printed Auxetic Structures for Advanced Concrete Reinforcement

Advanced Materials Interfaces
Reinforced concrete remains integral to modern infrastructure, yet traditional designs, relying on longitudinal reinforcing bars and stirrups, face limitations in adaptability and performance optimization.
Mobin Vandadi, Sara Heidarnezhad, Pardis Pourhaji, Nima Rahbar   +3 more
doaj   +1 more source

Structural Dynamic Analysis of Semi-Submersible Floating Vertical Axis Wind Turbines

Energies, 2016
The strong and stable wind at offshore locations and the increasing demand for energy have made the application of wind turbines in deeper water surge.
Jeremiah Ishie, Kai Wang, Muk Chen Ong
doaj   +1 more source

Study of a Flexible UAV Proprotor [PDF]

, 2013
This paper is concerned with the evaluation of design techniques, both for the propulsive performance and for the structural behavior of a composite flexible proprotor.
Bénard, Emmanuel, Lv, Peng, Mohd Zawawi, Fazila, Morlier, Joseph, Moschetta, Jean-Marc, Prothin, Sebastien   +5 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Combustion: Structural interaction in a viscoelastic material [PDF]

The effect of interaction between combustion processes and structural deformation of solid propellant was considered. The combustion analysis was performed on the basis of deformed crack geometry, which was determined from the structural analysis. On the
Chang, J. P., Chang, T. Y., Kumar, M., Kuo, K. K.   +3 more
core   +1 more source