Results 91 to 100 of about 3,903,891 (291)

Ultra-lightweight living structural material for enhanced stiffness and environmental sensing. [PDF]

open access: yesMater Today Bio, 2023
Park H   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Potential contribution of high strength, high modulus aramid fibers to the commercial feasibility of lighter than air craft [PDF]

open access: yes, 1975
Kevlar aramid fiber, fabric, rope and cable performance are reviewed along with the economics relevant to the material, structural, and reliability aspects of lighter than air ...
Sturgeon, D. L. G., Venkatachalam, T. K.
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Modelling Cell Origami via a Tensegrity Model of the Cytoskeleton in Adherent Cells

open access: yesApplied Bionics and Biomechanics, 2019
Cell origami has been widely used in the field of three-dimensional (3D) cell-populated microstructures due to their multiple advantages, including high biocompatibility, the lack of special requirements for substrate materials, and the lack of damage to
Lili Wang, Weiyi Chen
doaj   +1 more source

Extrusion Printed Silk Fibroin Scaffolds with Post-mineralized Calcium Phosphate as a Bone Structural Material. [PDF]

open access: yesInt J Bioprint, 2022
Shi R   +9 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Çanakkale Kent Merkezindeki Anaokulu Bahçelerinin Peyzaj Unsurlarının İncelenmesi

open access: yesDüzce University Faculty of Forestry Journal of Forestry
Okul öncesi eğitim dönemi bireyin yaşama dair en zengin deneyimlere sahip olduğu dönemdir ve içinde bulunduğu ortamın katacağı yaşantılar bireyin sonraki yaşamını önemli ölçüde etkiler. Bu dönem çocuğunun sağlıklı gelişimi için doğa mutlaka eğitim süreci
Seda Uygun, Özgür Kahraman
doaj   +1 more source

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