Results 211 to 220 of about 1,433,776 (263)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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Model Structure

2019
This chapter describes the logical structure of the proposed tunnel risk analysis model. In particular, the event tree technique for estimating the frequencies of the accidental scenarios and the procedure for defining the location of the accidental scenarios along the tunnel are illustrated.
Borghetti F., Cerean P., Derudi M., Frassoldati A.   +3 more
openaire   +2 more sources

THE STRUCTURE OF MACROECONOMIC MODELS

IFAC Proceedings Volumes, 1989
Abstract The specification of an macroeconomic model provides all information needed for a qualitative analysis of the model. Graph-theoretic concepts, like strongly connected components and minimal feedback sets, are used to determine optimal equation orderings and model blocks.
Sterken, Elmer, Houtman, Martijn
openaire   +2 more sources

A model for the structure of nucleoprotamine

Journal of Ultrastructure Research, 1979
A model for the structure of nucleoprotamine is presented, based on dark-field and bright-field electron micrographs of complexes of fish protamine and λDNA reconstituted in vitro . It is proposed that the protamine molecule, an ellipsoidal molecule with a comb- or star-shaped appearance, acts as a core around which the DNA double helix is wound or ...
D P, Bazett-Jones, F P, Ottensmeyer
openaire   +2 more sources

Protein Structure Modeling with MODELLER

2008
Genome sequencing projects have resulted in a rapid increase in the number of known protein sequences. In contrast, only about one-hundredth of these sequences have been characterized using experimental structure determination methods. Computational protein structure modeling techniques have the potential to bridge this sequence-structure gap.
Narayanan, Eswar, David, Eramian, Ben, Webb, Min-Yi, Shen, Andrej, Sali   +4 more
openaire   +2 more sources

Modeling the structure of the ribosome

Biochemistry and Cell Biology, 1995
Considering the size and complexity of the ribosome and the growing body of data from a wide range of experiments on ribosomal structure, it is becoming increasingly important to develop tools that facilitate the development of reliable models for the ribosome.
Easterwood, Thomas R., Harvey, Stephen C.   +1 more
openaire   +2 more sources

A Structural Model of Shape

IEEE Transactions on Pattern Analysis and Machine Intelligence, 1980
Shape description and recognition is an important and interesting problem in scene analysis. Our approach to shape description is a formal model of a shape consisting of a set of primitives, their properties, and their interrelationships. The primitives are the simple parts and intrusions of the shape which can be derived through the graph-theoretic ...
openaire   +3 more sources

Modelling Musical Structures

Constraints, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources