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How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
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Promotion or suppression of hydrogen evolution activity? The competition between sodium cations and quaternary ammonium ions at the metal/water interface. [PDF]
Chem SciBo S +5 more
europepmc +1 more source
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THE STRUCTURE OF MACROECONOMIC MODELS
IFAC Proceedings Volumes, 1989Abstract The specification of an macroeconomic model provides all information needed for a qualitative analysis of the model. Graph-theoretic concepts, like strongly connected components and minimal feedback sets, are used to determine optimal equation orderings and model blocks.
Sterken, Elmer, Houtman, Martijn
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2019
This chapter describes the logical structure of the proposed tunnel risk analysis model. In particular, the event tree technique for estimating the frequencies of the accidental scenarios and the procedure for defining the location of the accidental scenarios along the tunnel are illustrated.
Borghetti F. +3 more
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This chapter describes the logical structure of the proposed tunnel risk analysis model. In particular, the event tree technique for estimating the frequencies of the accidental scenarios and the procedure for defining the location of the accidental scenarios along the tunnel are illustrated.
Borghetti F. +3 more
openaire +2 more sources
2015 IEEE International Conference on Computer Vision (ICCV), 2015
This paper presents a novel 3D modeling framework that reconstructs an indoor scene as a structured model from panorama RGBD images. A scene geometry is represented as a graph, where nodes correspond to structural elements such as rooms, walls, and objects. The approach devises a structure grammar that defines how a scene graph can be manipulated.
Satoshi Ikehata +2 more
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This paper presents a novel 3D modeling framework that reconstructs an indoor scene as a structured model from panorama RGBD images. A scene geometry is represented as a graph, where nodes correspond to structural elements such as rooms, walls, and objects. The approach devises a structure grammar that defines how a scene graph can be manipulated.
Satoshi Ikehata +2 more
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IEEE Transactions on Pattern Analysis and Machine Intelligence, 1980
Shape description and recognition is an important and interesting problem in scene analysis. Our approach to shape description is a formal model of a shape consisting of a set of primitives, their properties, and their interrelationships. The primitives are the simple parts and intrusions of the shape which can be derived through the graph-theoretic ...
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Shape description and recognition is an important and interesting problem in scene analysis. Our approach to shape description is a formal model of a shape consisting of a set of primitives, their properties, and their interrelationships. The primitives are the simple parts and intrusions of the shape which can be derived through the graph-theoretic ...
openaire +2 more sources
Protein Structure Modeling with MODELLER
2008Genome sequencing projects have resulted in a rapid increase in the number of known protein sequences. In contrast, only about one-hundredth of these sequences have been characterized using experimental structure determination methods. Computational protein structure modeling techniques have the potential to bridge this sequence-structure gap.
Narayanan, Eswar +4 more
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