Results 71 to 80 of about 484,377 (242)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Unifying Structural Proximity and Equivalence for Network Embedding
The fundamental purpose of network embedding is to automatically encode each node in a network as a low-dimensional vector, while at the same time preserving certain characteristics of the network.
Benyun Shi +4 more
doaj +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Dynamics-based centrality for general directed networks
Determining the relative importance of nodes in directed networks is important in, for example, ranking websites, publications, and sports teams, and for understanding signal flows in systems biology.
A. Berman +12 more
core +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Flexible construction of hierarchical scale-free networks with general exponent
Extensive studies have been done to understand the principles behind architectures of real networks. Recently, evidences for hierarchical organization in many real networks have also been reported.
A. Wagner +9 more
core +1 more source
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Enhance synchronizability by structural perturbations
In this paper, we investigate the collective synchronization of system of coupled oscillators on Barab\'{a}si-Albert scale-free network. We propose an approach of structural perturbations aiming at those nodes with maximal betweenness.
B. Waxman +5 more
core +1 more source
Structure of node polynomials for curves on surfaces [PDF]
We provide a structural generalization of a theorem by Kleiman–Piene, concerning the enumerative geometry of nodal curves in a complete linear system on a smooth projective surface S. Provided that r, the number of nodes, is sufficiently small compared to the ampleness of the linear system, we show that, under certain assumptions, the number of r ...
openaire +3 more sources
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source

