Results 21 to 30 of about 1,140,542 (305)
Performance-based optimization of structures: theory and applications [PDF]
, 2005 Performance-based Optimization of Structures introduces a method to bridge the gap between optimization theory and its practical applications to structural engineering.
Liang, Qing Quan
core
, 2018 A simple scheme for avoiding non-spherical double counting in the combination of density func- tional theory with dynamical mean-field theory (DFT+DMFT)is developed.
Kristanovski, Oleg +3 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Risk Assessment Framework for Structural Failures of Polar Ship Under Ice Loads
Journal of Marine Science and EngineeringFor polar ships, navigation in ice-covered regions can lead to high risk to structural safety. To study the structural risk induced by ice loads, a risk assessment framework is proposed based on a probabilistic analysis.
Kai Sun +3 more
doaj +1 more source
Using Functional Programming to recognize Named Structure in an Optimization Problem: Application to Pooling [PDF]
, 2016 Branch-and-cut optimization solvers typically apply generic algorithms, e.g., cutting planes or primal heuristics, to expedite performance for many mathematical optimization problems.
Ceccon, F, Kouyialis, G, Misener, R
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
MoleculesWe report a step-economic strategy for the direct synthesis of novel polycyclic N-heterocycle-fused naphthoquinones by merging intramolecular oxidative coupling and cascade [4 + 2] cycloaddition.
Yu Dong +9 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
"Structural optimization may be defined in various ways. One definition could be the design and construction of a quality structure at the lowest cost. This definition often turns out to be inappropriate due to both the difficulty of giving a precise definition to cost and the dependence of the cost function on highly variable factors.
Adithya Challapalli, Guoqiang Li
+5 more sources