Results 31 to 40 of about 363,839 (268)

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Cut layout optimization for design of kirigami metamaterials under large stretching

Theoretical and Applied Mechanics Letters
Kirigami metamaterials have gained increasing attention due to their unusual mechanical properties under large stretching. However, most metamaterial designs obtained with trial-and-error approaches tend to lose their desirable properties under large ...
Chen Du, Yiqiang Wang, Zhan Kang
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Stimulation Modalities in Wearable Haptic Systems: Single-Mode Feedback to Multiphysics Actuation

Research
Wearable haptic systems enable natural and intuitive human–machine interaction, with growing relevance in immersive entertainment, physical rehabilitation, social communication, and personalized therapy.
Xu Guo, Raudel Avila, Ziqi Wu, Xinning Wang, Peixin Xu, Pengbin Ju, Qinzhe Yang, Pei Liu, Sherry Choi, Nikitsin Andrei, Zhaoqian Xie   +10 more
doaj   +1 more source

Symplectic superposition solutions for free in-plane vibration of orthotropic rectangular plates with general boundary conditions

Scientific Reports, 2023
This work reports new analytic free in-plane vibration solutions for orthotropic non-Lévy-type rectangular plates, i.e., those without two opposite edges simply supported, by the symplectic superposition method (SSM), which has never been applied to in ...
Zhaoyang Hu, Jingyu Du, Mingfeng Liu, Yihao Li, Zixuan Wang, Xinran Zheng, Tinh Quoc Bui, Rui Li   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Machine tool FEM model correction assisted by dynamic evolution sequence

Scientific Reports
In the simulation analysis of large-scale industrial instruments such as machine tools, in order to ensure simulation accuracy, model parameter correction is necessary. This research presents a machine tool model correction method assisted by the dynamic
Weihao Lin, Peng Zhong, Xindi Wei, Li Zhu, Xuanlong Wu   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source