Results 201 to 210 of about 116,856 (306)

Picolinamide-functionalized macrocyclic chelators for ^203/212Pb theranostic radiotracers.

Inorg Chem Front
Osborne BE, Siakalli C, Brown RK, White AJP, Rocco C, Weiss D, Delgado-Pinar E, García-España E, Sosabowski JK, Ma MT, Long NJ.   +10 more
europepmc   +1 more source

Benchmarking major somatic structural variant callers on the HG008 genome. [PDF]

Front Genet
Cui X, Liu Y, Qian L, Wang Y.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Multimodal electron microscopy of halide perovskite interfacial dynamics. [PDF]

Nature
Li X, Gu Q, Huang W, Fairclough SM, Friend RH, Stranks SD, Liu T, Ducati C.   +7 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

A Pathophysiology-Oriented Imaging Phenotype Framework for Nonobstructive Coronary Artery Disease. [PDF]

J Cardiovasc Dev Dis
Du H, Chen W, Tian H, Huang H, Wu Y, Liu J, Qiao H.   +6 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Manipulating Atomic Disorder and Mesoscale Architectures for High-Efficiency Thermoelectric Modules. [PDF]

Adv Sci (Weinh)
Xin J, Wang B, Xu C, Li W, Zhang P, Yang D, Wang Y, Dong J, Wei L, Zhang T, Jiang Q.   +10 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source