Results 61 to 70 of about 238,779 (294)

A comprehensive framework for operationalizing structural racism in health research: The association between mass incarceration of Black people in the U.S. and adverse birth outcomes

SSM: Population Health, 2022
Structural racism represents a key determinant of the racial health disparities that has characterized the U.S. population throughout its existence. While this reality has recently begun to gain increasing acknowledgment and acceptance within the health ...
Anders Larrabee Sonderlund, Mia Charifson, Robin Ortiz, Maria Khan, Antoinette Schoenthaler, Natasha J. Williams   +5 more
doaj   +1 more source

Changing the Rules of the Game: Youth Development & Structural Racism [PDF]

, 2005
With support of the Ford Foundation, the Philanthropic Initiative for Racial Equity (PRE) and mosaic consulting embarked on an 18-month study into the ways select community organizations engage youth in confronting structural racism.
Daniel HoSang, Julie Quiroz-Martinez, Lori Villarosa   +2 more
core  

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Structural Racism as a Contributor to Lung Cancer Incidence and Mortality Rates Among Black Populations in the United States

Cancer Control
Background Although racial disparities in lung cancer incidence and mortality have diminished in recent years, lung cancer remains the second most diagnosed cancer among US Black populations.
Joelle N. Robinson-Oghogho PhD, MPH, Kassandra I. Alcaraz PhD, MPH, Roland J. Thorpe PhD, MS   +2 more
doaj   +1 more source

‘They’ve all endorsed it…but I’m just not there:’ a qualitative exploration of COVID-19 vaccine hesitancy reported by Black and Latinx individuals

BMJ Open, 2023
Objective We sought to examine reasons for vaccine hesitancy among online communities of US-based Black and Latinx communities to understand the role of historical racism, present-day structural racism, medical mistrust and individual concerns about ...
David Scales, Sara Gorman, Savannah Windham, William Sandy, Nellie Gregorian, Lindsay Hurth, Malavika Radhakrishnan, Azubuike Akunne, Jack M Gorman   +8 more
doaj   +1 more source

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

Advanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park, Yidam Song, Hyun‐Woo Choi, Jaeuk Sung, Harin Jin, WonSeok Gwak, Kirim Yoo, Soohwang Lee, Jongeon Park, Jeongmin Kim, Hye‐Jun Jo, Jahyun Koo, Youngdo Jeong, Kwan Hyi Lee, Seung‐Jung Kee, Hojun Kim   +15 more
wiley   +1 more source

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy, Jichuan Wu, Serena Omo‐Lamai, Liuqian Wang, Fengyi Dong, Aleksa Milosavljevic, Sarah O'Neill, Taylor Brysgel, Yufei Wang, Michael Zaleski, Emily Wolfe, Rhea Maheshwari, Manthan Patel, Dirk Trauner, Jia Nong, Zhicheng Wang, Jacob S. Brenner   +16 more
wiley   +1 more source

A Fair Go for All: A Problematic Contribution to Anti-racism Praxis in Aotearoa [PDF]

, 2013
In New Zealand, the Human Rights Commission is the lead agency in countering institutional racism. They have recently undertaken a major research project, A Fair Go For All (Human Rights Commission 2011), to inform the development of a national strategy ...
Came, H
core  

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Advancing Racial Equity in Communities: Lessons for Philanthropy [PDF]

, 2010
Outlines elements of success and lessons learned from efforts by foundations and nonprofits in five communities to help dismantle the structural racism perpetuating disparities in income, wealth, education, housing, employment, and criminal ...
Mary Virtue
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