Results 131 to 140 of about 3,620,319 (299)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

From Practice to Transformation: Regrounding Community-Based Adaptation in Critical Realism

open access: yesSocial Sciences
Community-based adaptation (CBA) has become a credible remedy to climate change adaptation, emphasizing local participation and community-defined priorities.
Paul Strikker, Tom Selje, Boris Heinz
doaj   +1 more source

On the Ontology of Structural Realism

open access: yesOpen Journal of Political Science, 2019
Due to its systemic approach, structural realism (or neorealism) can be subsumed under methodological holism, which takes social phenomena to be wholes that cannot be reduced to their parts. The wholes posited by structural realism are the state and the international structure.
openaire   +2 more sources

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

‘What is a realistic forecast?’ Assessing data-driven weather forecasts, a journey from verification to falsification

open access: yesEnvironmental Research Communications
The artificial intelligence revolution is fuelling a paradigm shift in weather forecasting: forecasts are generated with machine learning models trained on large datasets rather than with physics-based numerical models that solve partial differential ...
Zied Ben Bouallègue
doaj   +1 more source

Alþjóðaöryggismál: umræða um hugmyndir og kenningar

open access: yesNordicum-Mediterraneum
The paper discusses international security based on ideas about the role of the state, human nature, war and historical memory. International security studies and two theories of international relations, neo-realism (e.
Jakob Þór Kristjánsson
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Science and Reality [PDF]

open access: yes, 2006
Scientific realism is the view that the aim of science is to produce true or approximately true theories about nature. It is a view which not only is shared by many philosophers but also by scientists themselves.
Faye, Jan
core  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

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